سعر بيكسوناميد 14مجم 30 قرص 2026

Teriflunomide 14 mg oral tablets, pack of 30; pyrimidine-synthesis inhibitor immunomodulator for relapsing multiple sclerosis.

• Relapsing forms of multiple sclerosis (clinically isolated syndrome, relapsing-remitting disease, active secondary progressive disease)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common: headache, diarrhea, nausea, alopecia and increased ALT.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Severe hepatic impairment; pregnancy and females of reproductive potential not using effective contraception; hypersensitivity; current leflunomide treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: hepatotoxicity (including acute liver failure) and embryofetal toxicity. Obtain transaminases and bilirubin within 6 months before starting and monitor during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Elimination is slow (about 8 months, up to 2 years); an accelerated elimination procedure can be used. Also: hypersensitivity, serious skin reactions, peripheral neuropathy, increased blood pressure, interstitial lung disease.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy and in females of reproductive potential not using effective contraception because of the potential for fetal harm.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No human data; women should not breastfeed during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Teriflunomide: Immunomodulatory agent that inhibits dihydroorotate dehydrogenase, a mitochondrial enzyme of de novo pyrimidine synthesis; may reduce the number of activated lymphocytes in the CNS.