دواعي استعمال بوتاسبيرونو 25مجم 20 قرص

Spironolactone 25 mg tablets, 20 per pack; an aldosterone antagonist (potassium-sparing diuretic).

• NYHA class III-IV heart failure with reduced ejection fraction (survival, edema, hospitalization).DailyMed (US National Library of Medicine)
• Add-on treatment of hypertension.DailyMed (US National Library of Medicine)
• Edema in cirrhosis or nephrotic syndrome when other measures are inadequate.DailyMed (US National Library of Medicine)
• Primary hyperaldosteronism.DailyMed (US National Library of Medicine)

• Hyperkalemia; Addison's disease; concomitant use of eplerenone.نشرة دولية لنفس التركيبة · DailyMed (US National Library of Medicine)

• Can cause hyperkalemia, especially with renal impairment, potassium supplements/salt substitutes, ACE inhibitors or ARBs.نشرة دولية لنفس التركيبة · DailyMed (US National Library of Medicine)
• Hypotension and worsening renal function; electrolyte and metabolic abnormalities; gynecomastia.نشرة دولية لنفس التركيبة · DailyMed (US National Library of Medicine)

• Potassium supplements, potassium-containing salt substitutes, ACE inhibitors, ARBsIncreased risk of hyperkalemia.DailyMed (US National Library of Medicine)

• Based on mechanism and animal data, spironolactone may affect sex differentiation of the male fetus; avoid use in pregnancy where possible (US label).نشرة دولية لنفس التركيبة · DailyMed (US National Library of Medicine)
• Active metabolite canrenone found in breast milk in low amounts expected to be clinically inconsequential; long-term infant effects unknown.نشرة دولية لنفس التركيبة · DailyMed (US National Library of Medicine)

• Monitor serum potassium within one week of initiation and regularly thereafter; monitor volume status, renal function, electrolytes, uric acid and blood glucose periodically.نشرة دولية لنفس التركيبة · DailyMed (US National Library of Medicine)