سعر برولوتكس 25مجم حقن تحت الجلد 7 فيال 2025

Progesterone 25 mg solution for subcutaneous injection (Prolutex, IBSA, Switzerland; agent Habib Scientific Office), pack of 7 vials; used for progesterone supplementation/luteal support in assisted reproduction.

• Luteal support as part of an assisted reproductive technology (ART) programme in adult infertile women who cannot use or tolerate vaginal preparationsPopulation: Adult womenCBG-MEB (Medicines Evaluation Board, Netherlands)
• Progesterone hormone - gynaecology (directory listing)

• Very common: uterine spasm, vaginal bleeding. Common: headache, abdominal distension and pain, nausea, vomiting, constipation, breast tenderness and pain, injection-site reactions. Uncommon: mood changes, dizziness, somnolence, pruritus, rash.International label, equivalent formulation · CBG-MEB (Medicines Evaluation Board, Netherlands)

• Hypersensitivity; undiagnosed vaginal bleeding; known missed abortion or ectopic pregnancy; severe hepatic dysfunction; known or suspected breast or genital tract cancer; active or past arterial/venous thromboembolism or severe thrombophlebitis; porphyria; history of idiopathic jaundice, severe pruritus or pemphigoid gestationis in pregnancy.International label, equivalent formulation · CBG-MEB (Medicines Evaluation Board, Netherlands)

• Stop if myocardial infarction, cerebrovascular disease, thromboembolism, thrombophlebitis or retinal thrombosis is suspected; monitor patients with depression, fluid-retention-sensitive conditions and diabetes; abrupt withdrawal may cause anxiety, mood changes and increased seizure susceptibility; may cause drowsiness/dizziness.International label, equivalent formulation · CBG-MEB (Medicines Evaluation Board, Netherlands)

• CYP3A4 inducers (e.g. rifampicin, carbamazepine, phenobarbital, phenytoin, St John's wort)May reduce progesterone bioavailability.CBG-MEB (Medicines Evaluation Board, Netherlands)
• CYP3A4 inhibitors (e.g. ketoconazole)May increase progesterone bioavailability.CBG-MEB (Medicines Evaluation Board, Netherlands)
• CiclosporinProgestogens may inhibit ciclosporin metabolism, raising its levels and toxicity risk.CBG-MEB (Medicines Evaluation Board, Netherlands)

• Used for luteal support in ART; data on congenital anomalies after in-utero exposure are limited and inconclusive; rates in the clinical study were similar to the general population.International label, equivalent formulation · CBG-MEB (Medicines Evaluation Board, Netherlands)
• Progesterone is excreted in breast milk; Prolutex should not be used during breastfeeding.International label, equivalent formulation · CBG-MEB (Medicines Evaluation Board, Netherlands)