سعر ايالوجين بلس 25جم كريم 2022

Ialugen Plus cream 25 g (IBSA, Switzerland; Habib Scientific Office in Egypt): topical cream combining silver sulfadiazine (antibacterial/antifungal) with sodium hyaluronate (supports granulation and epithelialisation) for prevention and treatment of infected skin lesions such as wounds, ulcers, abrasions and burns.

• Prophylaxis and treatment of infected skin lesions: wounds, ulcers, abrasions and burns of any degreeSwissmedic AIPS (swissmedicinfo.ch)
• Under medical supervision only (not for self-medication): extensive or 2nd/3rd-degree burns, leg ulcers, anal wounds such as anal fissures and post-haemorrhoidectomy woundsSwissmedic AIPS (swissmedicinfo.ch)

• Mostly reversible application-site skin changes: erythema, eczema, pruritus, dermatitis, skin discoloration, photosensitivity, oedema; hypersensitivity reactions (generalised rash). With large treated areas, systemic sulfonamide/silver effects (e.g. leukopenia, thrombocytopenia, agranulocytosis, methaemoglobinaemia, toxic hepatitis, renal failure, severe skin reactions) cannot be excluded.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)

• Premature and newborn infants and infants up to 2 months; third trimester of pregnancy; hypersensitivity to the active substances or excipients.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)

• Systemic absorption of sulfadiazine and silver is possible, especially with large-area or long-term use.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)
• Use with caution and monitor blood count in known or suspected G6PD deficiency (haemolysis risk); caution in acute porphyria and in slow CYP2C9 metabolisers.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)
• Leukopenia (mainly neutropenia) has been observed with silver sulfadiazine; check white cell count with prolonged use or suggestive symptoms.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)

• Drugs interacting with sulfonamides (CYP2C9 inhibition; plasma-protein displacement)About 10% of sulfadiazine is absorbed; sulfonamide-type interactions cannot be excluded: salicylates, indometacin and phenylbutazone may enhance sulfadiazine, and sulfadiazine may enhance anticoagulants, methotrexate, sulfonylureas and thiopental.Swissmedic AIPS (swissmedicinfo.ch)
• Topical proteolytic enzymesInactivated by the silver component when applied concomitantly.Swissmedic AIPS (swissmedicinfo.ch)

• Sulfadiazine crosses the placenta; potential human risk unknown. Contraindicated in the third trimester (risk of neonatal kernicterus); in the first and second trimesters use only if benefit outweighs risk.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)
• No data on passage into milk; other sulfonamides pass in small amounts. Use during breastfeeding is not recommended; never apply to the breast area; infants with hyperbilirubinaemia or G6PD deficiency should not be breastfed during use.International label, same product · Swissmedic AIPS (swissmedicinfo.ch)

• Silver sulfadiazine: Active against many Gram-positive and Gram-negative bacteria (e.g. S. aureus, E. coli, Enterobacter, Pseudomonas aeruginosa) and some fungi; exact mechanism unknown (Swiss professional information).
• Sodium hyaluronate: Exogenous hyaluronic acid has anti-inflammatory activity and accelerates granulation tissue formation, favouring epithelialisation and scarring (Swiss professional information).