دواعي استعمال كوانتاماش 4مجم 12 كيس

Cholestyramine 4 g sachets (12 per pack); bile acid sequestrant used to lower cholesterol.

• Adjunct to diet to reduce elevated serum cholesterol in primary hypercholesterolaemia (elevated LDL-C) not adequately responsive to dietالفئة: AdultsDailyMed (NLM)

• Most common: constipation. Less frequent: abdominal discomfort/pain, flatulence, nausea, vomiting, diarrhoea, eructation, anorexia, steatorrhoea, bleeding tendency, vitamin A and D deficiency, hyperchloraemic acidosis in children, osteoporosis, skin rash/irritation; rare intestinal obstruction.نشرة دولية لنفس التركيبة · DailyMed (NLM)

• Complete biliary obstruction where bile is not secreted into the intestine; hypersensitivity to any component.نشرة دولية لنفس التركيبة · DailyMed (NLM)

• Chronic use may cause bleeding tendency from vitamin K deficiency (hypoprothrombinaemia), reduced folate, and hyperchloraemic acidosis (especially in younger/smaller patients); caution in renal insufficiency, volume depletion or with spironolactone; may cause or worsen constipation.نشرة دولية لنفس التركيبة · DailyMed (NLM)

• Concomitant oral drugs (e.g., warfarin, thiazide diuretics, propranolol, tetracycline, penicillin G, phenobarbital, thyroid hormones, oestrogens/progestins, digitalis)Cholestyramine may delay or reduce their absorption; discontinuing cholestyramine can be hazardous if a drug such as digitalis was titrated during co-therapy.DailyMed (NLM)
• Fat-soluble vitamins (A, D, E, K)Binding of bile acids may impair fat digestion and absorption of fat-soluble vitamins.DailyMed (NLM)

• Not absorbed systemically but interferes with absorption of fat-soluble vitamins, so prenatal supplementation may be inadequate; weigh benefits against risks in pregnancy.نشرة دولية لنفس التركيبة · DailyMed (NLM)
• Use with caution in nursing mothers; reduced maternal vitamin absorption may affect the nursing infant.نشرة دولية لنفس التركيبة · DailyMed (NLM)