سعر رازانتامين 8مجم 10 كبسول 2022

Galantamine 8 mg extended-release capsules (acetylcholinesterase inhibitor) for Alzheimer's dementia; 10 capsules, Aug Pharma.

• Mild to moderate dementia of the Alzheimer's typePopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (at least 5% and twice placebo): nausea, vomiting, diarrhoea, dizziness, headache and decreased appetite.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to galantamine hydrobromide or any excipient.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Serious skin reactions (Stevens-Johnson syndrome, acute generalized exanthematous pustulosis); discontinue at first appearance of rash.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Vagotonic effects: bradycardia and heart block, including in patients without known conduction abnormalities.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Increased gastric acid secretion; monitor for active or occult gastrointestinal bleeding, especially with ulcer history or NSAIDs.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anticholinergic medicationsGalantamine may interfere with their activity.DailyMed (U.S. National Library of Medicine)
• Succinylcholine-type muscle relaxants and other cholinergic agonists/cholinesterase inhibitorsSynergistic effect expected.DailyMed (U.S. National Library of Medicine)
• Paroxetine (strong CYP2D6 inhibitor)Increased galantamine oral bioavailability by about 40%.DailyMed (U.S. National Library of Medicine)

• No adequate data in pregnant women; developmental toxicity in animal studies at clinically relevant doses; may cause fetal harm.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk, effects on breastfed infant or milk production.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Galantamine: Reversible, competitive acetylcholinesterase inhibitor, thought to enhance cholinergic function (US label).