سعر مانتين 10مجم 30 قرص 2025

Memantine 10 mg film-coated tablets, box of 30, by ADWIA (Egypt); NMDA receptor antagonist for Alzheimer's dementia.

• Treatment of moderate to severe dementia of the Alzheimer's type.DailyMed (U.S. National Library of Medicine)

• Most common (at least 5% and more than placebo): dizziness, headache, confusion and constipation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to memantine hydrochloride or any excipient.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Conditions that raise urine pH (e.g. renal tubular acidosis, severe urinary infection, alkalinising drugs or diet) may reduce memantine elimination and raise plasma levels.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Drugs that alkalinise urine (carbonic anhydrase inhibitors, sodium bicarbonate)Memantine clearance falls by about 80% at urine pH 8; use with caution.DailyMed (U.S. National Library of Medicine)
• Other NMDA antagonists (amantadine, ketamine, dextromethorphan)Combination not systematically evaluated; use with caution.DailyMed (U.S. National Library of Medicine)

• No adequate human data; animal studies at doses above human exposure showed reduced offspring body weight and ossification.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Memantine: Postulated to act as a low-to-moderate affinity uncompetitive (open-channel) NMDA receptor antagonist, reducing effects of persistent glutamatergic activation.