سعر ريسباتيو 20مجم 20 قرص 2024

Sildenafil 20 mg film-coated tablets, pack of 20 (2 strips), marketed in Egypt by Marcyrl / Pharma Right Group.

• Treatment of pulmonary arterial hypertension (WHO Group I) in adults to improve exercise ability and delay clinical worseningPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of PAH (WHO Group I) in pediatric patients 1 to 17 years oldPopulation: Pediatric 1-17 yearsDailyMed (U.S. National Library of Medicine)

• Adults: headache, dyspepsia, flushing, pain in limb, myalgia, back pain and diarrhoea.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Concomitant use of organic nitrates in any form (risk of hypotension).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant use of riociguat.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Known hypersensitivity to sildenafil or any product component.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Vasodilatory effect with mild transient blood pressure decrease; consider patients on antihypertensives, with resting hypotension, fluid depletion, LV outflow obstruction or autonomic dysfunction.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not recommended in pulmonary veno-occlusive disease; consider PVOD if pulmonary oedema occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Label also warns of vision loss, hearing loss and priapism.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• NitratesConcomitant use contraindicated.DailyMed (U.S. National Library of Medicine)
• Strong CYP3A inhibitorsConcomitant use not recommended.DailyMed (U.S. National Library of Medicine)
• Moderate-to-strong CYP3A inducers (e.g. bosentan)Decrease sildenafil exposure; dose up-titration may be needed.DailyMed (U.S. National Library of Medicine)

• Limited published data do not report a clear association of sildenafil with major birth defects, miscarriage or adverse maternal/fetal outcomes; untreated PAH carries maternal and fetal risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Sildenafil and its active metabolite have been found in human milk (case report); insufficient information on effects on the breastfed infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Sildenafil: Inhibits cGMP-specific PDE-5, increasing cGMP in vascular smooth muscle and causing relaxation/vasodilation (pulmonary vascular bed per the US Revatio label).