سعر ريماكتان 2% شراب 50 مل 2022

Rimactane 2% syrup (rifampicin 2%, 50 ml bottle) by Novartis, an Egyptian oral rifampicin liquid used as an antituberculosis antibiotic.

• Tuberculosis: in combination with other active anti-tuberculosis drugs, all forms including fresh, advanced, chronic and drug-resistant cases.electronic medicines compendium (emc)
• Leprosy (multibacillary and paucibacillary), with at least one other anti-leprosy drug.electronic medicines compendium (emc)
• Brucellosis, Legionnaires disease and serious staphylococcal infections, in combination with another appropriate antibiotic.electronic medicines compendium (emc)

• Gastrointestinal: heartburn, epigastric distress, anorexia, nausea, vomiting, jaundice, flatulence, cramps, diarrhoea; pseudomembranous colitis reported.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Thrombocytopenia with or without purpura (mainly with intermittent therapy), flu-like reactions, hepatitis and hyperbilirubinaemia, and severe skin reactions (SJS, TEN, DRESS, AGEP).International label, equivalent formulation · electronic medicines compendium (emc)

• Hypersensitivity to rifamycins or any excipient.International label, equivalent formulation · electronic medicines compendium (emc)
• Jaundice.International label, equivalent formulation · electronic medicines compendium (emc)
• Concurrent saquinavir/ritonavir.International label, equivalent formulation · electronic medicines compendium (emc)

• Hepatotoxicity ranging from asymptomatic enzyme rises to fulminant liver failure and death; monitor liver function, especially with liver disease or other hepatotoxic drugs, and discontinue if hepatic damage occurs or worsens.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Possible immunological reactions including anaphylaxis with intermittent therapy; patients should not interrupt dosing.International label, equivalent formulation · electronic medicines compendium (emc)
• Discolours urine, sweat, sputum, tears and teeth (yellow, orange, red or brown); soft contact lenses may be permanently stained.International label, equivalent formulation · electronic medicines compendium (emc)

• Hormonal contraceptivesRifampicin reduces contraceptive exposure; change to non-hormonal contraception.electronic medicines compendium (emc)
• AntacidsMay reduce rifampicin absorption; give rifampicin at least 1 hour before antacids.electronic medicines compendium (emc)
• CYP3A4/CYP2C/UGT/P-gp substrates (e.g. warfarin, ciclosporin, tacrolimus, azole antifungals, many antiretrovirals)Induction lowers their plasma levels and effect; dose adjustment or avoidance may be needed.electronic medicines compendium (emc)

• Teratogenic in animals at very high doses; no well-controlled human studies. Use in pregnancy only if the potential benefit justifies the potential risk to the fetus.International label, equivalent formulation · electronic medicines compendium (emc)
• Published data over decades of use have not established an association with major birth defects or miscarriage; teratogenic in rodents.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Rifampicin is excreted in breast milk; patients should not breast-feed unless the physician judges the benefit outweighs the risk to the infant.International label, equivalent formulation · electronic medicines compendium (emc)

• Rifampicin: Inhibits bacterial DNA-dependent RNA polymerase without affecting the mammalian enzyme.