سعر روتاسيستايين 20% محلول للتسريب الوريدي 25 مل 2024

Acetylcysteine 20% (200 mg/ml) solution for intravenous infusion, 25 ml; manufactured by Arabcomed-Egypt for Rotabiogen.

• Antidote to prevent or lessen hepatic injury after ingestion of a potentially hepatotoxic quantity of acetaminophen (acute or repeated supratherapeutic ingestion).Population: Adults and pediatric patients weighing 5 kg or moreDailyMed (U.S. National Library of Medicine)
• Mucolytic for thick bronchial secretions; antidote in paracetamol overdose (directory text).

• Most common (>2%): rash, urticaria/facial flushing and pruritus; acute hypersensitivity in about 17% in an infusion-rate study.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Previous hypersensitivity reaction to acetylcysteine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Serious hypersensitivity reactions including fatal anaphylaxis, rash, hypotension, wheezing and bronchospasm, usually soon after starting the infusion; monitor asthmatic patients closely.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Fluid overload: reduce total volume in patients under 40 kg and those needing fluid restriction.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Limited case data are insufficient to inform drug-associated risk; delaying treatment of acetaminophen overdose may increase maternal and fetal morbidity and mortality; animal studies showed no fetal harm.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk; nearly cleared 30 h after administration - breastfeeding women may pump and discard milk for 30 h.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Acetylcysteine: Probably protects the liver by maintaining or restoring glutathione or acting as an alternate substrate for conjugation of the reactive acetaminophen metabolite (US Acetadote label).