سعر روتابيريتيك 1جم/100مل فيال 1000 مجم/100 مل 2024

Paracetamol 1000 mg/100 ml (10 mg/ml) solution for intravenous infusion, 1 vial, by Grand Pharma > Biocapital Pharma.

• Management of mild to moderate pain, and of moderate to severe pain with adjunctive opioid analgesics, in adults and children 2 years and older.DailyMed (NLM)
• Reduction of fever in adult and paediatric patients.DailyMed (NLM)

• Most common in adults (≥5%): nausea, vomiting, headache and insomnia.International label, same formulation · DailyMed (NLM)

• Known hypersensitivity to paracetamol or excipients; severe hepatic impairment or severe active liver disease.International label, same formulation · DailyMed (NLM)

• Doses higher than recommended may cause hepatic injury including liver failure and death; use caution in hepatic impairment, alcoholism, chronic malnutrition, severe hypovolaemia or severe renal impairment (CrCl ≤30 mL/min).International label, same formulation · DailyMed (NLM)
• Rare serious skin reactions (AGEP, Stevens-Johnson syndrome, toxic epidermal necrolysis); discontinue at the first appearance of rash.International label, same formulation · DailyMed (NLM)

• WarfarinChronic oral paracetamol 4000 mg/day has raised INR in some warfarin-stabilised patients; more frequent INR assessment may be appropriate.DailyMed (NLM)
• CYP2E1 inducers / ethanolMay alter paracetamol metabolism and increase its hepatotoxic potential.DailyMed (NLM)

• Published epidemiological studies of oral paracetamol in pregnancy have not reported a clear association with birth defects, miscarriage or adverse maternal or fetal outcomes; no animal reproduction studies with IV paracetamol.International label, same formulation · DailyMed (NLM)

• Paracetamol (acetaminophen): Precise mechanism not established; thought to act mainly centrally (US OFIRMEV label).