سعر سيرفيكلازيد 80مجم 10 اقراص 2022

Gliclazide 80 mg tablets, pack of 10 (Serviclazid, Novartis, Egypt).

• Type 2 (non-insulin-dependent) diabetes mellitus when diet, exercise and weight loss alone are insufficientPopulation: AdultsElectronic medicines compendium (emc), Datapharm

• Hypoglycaemia is the most frequent adverse reaction, especially with irregular or skipped meals; gastrointestinal disturbances (abdominal pain, nausea, vomiting, dyspepsia, diarrhoea, constipation) have also been reported.International label, same formulation · Electronic medicines compendium (emc), Datapharm

• Hypersensitivity to gliclazide, other sulfonylureas, sulphonamides or excipients; type 1 diabetes; diabetic pre-coma, coma or ketoacidosis; severe renal or hepatic insufficiency; treatment with miconazole; lactation.International label, same formulation · Electronic medicines compendium (emc), Datapharm

• Hypoglycaemia, sometimes severe and prolonged, may occur; prescribe only if regular food intake (including breakfast) is likely. Risk is increased by irregular or missed meals, fasting, alcohol, strenuous exercise, renal or severe hepatic insufficiency, certain endocrine disorders, overdose and interacting drugs.International label, same formulation · Electronic medicines compendium (emc), Datapharm
• Dysglycaemia (hypo- and hyperglycaemia) has been reported with concomitant fluoroquinolones, especially in the elderly; monitor blood glucose carefully.International label, same formulation · Electronic medicines compendium (emc), Datapharm
• G6PD deficiency: sulfonylureas can cause haemolytic anaemia; use caution and consider a non-sulfonylurea alternative. Acute porphyria has been described with some other sulfonylureas.International label, same formulation · Electronic medicines compendium (emc), Datapharm

• Miconazole (systemic or oromucosal gel)Contraindicated: increases the hypoglycaemic effect, possibly to coma.Electronic medicines compendium (emc), Datapharm
• AlcoholNot recommended: increases hypoglycaemic reactions and can lead to hypoglycaemic coma; avoid alcohol and alcohol-containing medicines.Electronic medicines compendium (emc), Datapharm
• Phenylbutazone (systemic)Not recommended: increases the hypoglycaemic effect of sulfonylureas.Electronic medicines compendium (emc), Datapharm

• Limited data in pregnancy; as a precaution avoid gliclazide in pregnancy. Insulin is the drug of first choice; switch from oral hypoglycaemic therapy to insulin before a planned pregnancy or as soon as pregnancy is discovered.International label, same formulation · Electronic medicines compendium (emc), Datapharm
• Contraindicated during breastfeeding because of the risk of neonatal hypoglycaemia; excretion in milk is unknown.International label, same formulation · Electronic medicines compendium (emc), Datapharm

• Gliclazide: Stimulates insulin release from pancreatic beta cells and improves glucose tolerance.