سعر سيفوفلوران 100% سائل للاستنشاق 250 مل 2024

Sevoflurane 100% liquid for inhalation 250 ml: sevoflurane 100% volatile liquid for induction and maintenance of general anaesthesia via a sevoflurane-calibrated vaporiser; hospital use by anaesthetists (Arab Caps > Acdima International Trading, Egypt).

• Induction and maintenance of general anaesthesia in adults and children (inpatient and outpatient surgery).Population: Adults and childrenelectronic medicines compendium (emc)

• Very common adverse reactions in clinical trials and post-marketing use include agitation, bradycardia, hypotension, cough, nausea and vomiting; rare malignant hyperthermia and hepatic injury.International label, equivalent formulation · electronic medicines compendium (emc)

• Known or suspected genetic susceptibility to malignant hyperthermia.International label, equivalent formulation · electronic medicines compendium (emc)
• Known or suspected hypersensitivity to sevoflurane or other halogenated anaesthetics (e.g. unexplained liver dysfunction, fever or leucocytosis after such anaesthesia); history of confirmed hepatitis due to a halogenated inhalational anaesthetic or unexplained moderate-severe hepatic dysfunction with jaundice, fever and eosinophilia after sevoflurane.International label, equivalent formulation · electronic medicines compendium (emc)
• Patients in whom general anaesthesia is contraindicated.International label, equivalent formulation · electronic medicines compendium (emc)

• May trigger malignant hyperthermia in susceptible patients (rare, fatal cases reported): stop triggering agents, give IV dantrolene and supportive care.International label, equivalent formulation · electronic medicines compendium (emc)
• Rare perioperative hyperkalaemia with cardiac arrhythmias and death reported in paediatric patients, especially with neuromuscular disease (e.g. Duchenne) and concomitant succinylcholine.International label, equivalent formulation · electronic medicines compendium (emc)
• Very rare postoperative hepatic dysfunction or hepatitis; repeated exposure to halogenated hydrocarbons within a short interval may increase the risk.International label, equivalent formulation · electronic medicines compendium (emc)

• Adrenaline (epinephrine)Sevoflurane sensitises the myocardium to adrenaline-induced arrhythmias similarly to isoflurane (threshold about 5 micrograms/kg).electronic medicines compendium (emc)

• Limited data in pregnant women; animal studies showed reproductive toxicity, so use in pregnancy only if clearly needed. Safety shown for caesarean section; caution in obstetric anaesthesia because of uterine relaxation and increased uterine bleeding.International label, equivalent formulation · electronic medicines compendium (emc)
• Not known whether sevoflurane is excreted in human milk; use with caution in nursing women.International label, equivalent formulation · electronic medicines compendium (emc)

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