سعر ساكسينيل كولين كلوريد 100مجم/5مل 5 امبولات 2024

Succinylcholine chloride 100 mg/5 ml (20 mg/ml) solution for injection, 5 ampoules; short-acting depolarizing neuromuscular blocker.

• Adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilationPopulation: Adults and pediatric patientsDailyMed (U.S. National Library of Medicine)

• Clinically significant: hyperkalemic rhabdomyolysis with cardiac arrest in children, anaphylaxis, hyperkalemia, malignant hyperthermia, bradycardia, increased intraocular pressure, prolonged block (Phase II block) and tachyphylaxis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known or suspected genetic susceptibility to malignant hyperthermia; skeletal muscle myopathies; known hypersensitivity to succinylcholine; after the acute phase of major burns, multiple trauma, extensive denervation of skeletal muscle or upper motor neuron injury (risk of severe hyperkalemia).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING: ventricular dysrhythmias, cardiac arrest and death from hyperkalemic rhabdomyolysis in apparently healthy pediatric patients with undiagnosed myopathy (e.g. Duchenne); treat hyperkalemia immediately if cardiac arrest occurs; reserve pediatric use for emergency intubation.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• May trigger malignant hyperthermia in susceptible individuals (risk increased with volatile anesthetics); fatal outcomes reported.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Hyperkalemia may cause serious arrhythmias or cardiac arrest in patients with electrolyte abnormalities or digitalis toxicity; increased risk in chronic abdominal infection, subarachnoid hemorrhage or degenerative nervous system conditions.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Published data over decades have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; commonly used for caesarean section; risk of prolonged apnea in some pregnant women during labor and delivery.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human or animal milk or effects on the breastfed infant; weigh benefits of breastfeeding against clinical need.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)