تخطَّ إلى المحتوى
دليل الأدوية المصري
تابع آخر تحديثات الأسعار على واتساب

سعر تاموكسيفين اكديما 10مجم 30 اقراص 2022

Tamoxifen-acdima 10mg 30 tab

معلومات الدواء

التفاصيل الكاملة
دواعي الاستعمالUses
  • Treatment of metastatic breast cancer in women and men; in premenopausal women an alternative to oophorectomy or ovarian irradiation (benefit more likely in estrogen-receptor-positive tumours).الفئة: AdultsDailyMed (U.S. National Library of Medicine)
  • Adjuvant treatment of node-positive and axillary node-negative breast cancer following surgery and radiation.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
  • Reduction of the risk of invasive breast cancer in women with ductal carcinoma in situ (DCIS) after surgery and radiation, and in women at high risk of breast cancer.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
  • Treatment of metastatic breast cancer in women and men; in premenopausal women an alternative to oophorectomy or ovarian irradiation (benefit more likely in estrogen-receptor-positive tumours).Population: AdultsDailyMed (U.S. National Library of Medicine)
  • Adjuvant treatment of node-positive and axillary node-negative breast cancer following surgery and radiation.Population: AdultsDailyMed (U.S. National Library of Medicine)
  • Reduction of the risk of invasive breast cancer in women with ductal carcinoma in situ (DCIS) after surgery and radiation, and in women at high risk of breast cancer.Population: AdultsDailyMed (U.S. National Library of Medicine)
الآثار الجانبيةSide effects
  • Most frequent adverse reaction in metastatic breast cancer is hot flashes; others include hypercalcaemia, peripheral oedema, distaste for food, pruritus vulvae, depression, dizziness, light-headedness, headache, hair thinning and vaginal dryness.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • Most frequent adverse reaction in metastatic breast cancer is hot flashes; others include hypercalcaemia, peripheral oedema, distaste for food, pruritus vulvae, depression, dizziness, light-headedness, headache, hair thinning and vaginal dryness.International label, same formulation · DailyMed (U.S. National Library of Medicine)
موانع الاستعمالContraindications
  • Known hypersensitivity to tamoxifen or any ingredient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • In risk-reduction settings (high-risk women and DCIS): women requiring concomitant coumarin-type anticoagulant therapy or with a history of deep vein thrombosis or pulmonary embolism.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • Known hypersensitivity to tamoxifen or any ingredient.International label, same formulation · DailyMed (U.S. National Library of Medicine)
  • In risk-reduction settings (high-risk women and DCIS): women requiring concomitant coumarin-type anticoagulant therapy or with a history of deep vein thrombosis or pulmonary embolism.International label, same formulation · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطاتWarnings & precautions
  • Boxed warning: uterine malignancies (endometrial adenocarcinoma and uterine sarcoma), stroke and pulmonary embolism, some fatal, reported in the risk-reduction setting; benefits should be weighed against risks.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • Hypercalcaemia may occur in patients with bone metastases within weeks of starting therapy; discontinue if severe.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • Thromboembolic events (deep vein thrombosis, pulmonary embolism), cataracts and liver abnormalities are described in the label warnings.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • Boxed warning: uterine malignancies (endometrial adenocarcinoma and uterine sarcoma), stroke and pulmonary embolism, some fatal, reported in the risk-reduction setting; benefits should be weighed against risks.International label, same formulation · DailyMed (U.S. National Library of Medicine)
  • Hypercalcaemia may occur in patients with bone metastases within weeks of starting therapy; discontinue if severe.International label, same formulation · DailyMed (U.S. National Library of Medicine)
  • Thromboembolic events (deep vein thrombosis, pulmonary embolism), cataracts and liver abnormalities are described in the label warnings.International label, same formulation · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائيةDrug interactions
  • Coumarin-type anticoagulants (warfarin)Significant increase in anticoagulant effect may occur; careful monitoring of prothrombin time required; contraindicated in risk-reduction use.DailyMed (U.S. National Library of Medicine)
  • Rifampin, aminoglutethimide (CYP3A4 inducers)Reduce plasma tamoxifen and N-desmethyl tamoxifen concentrations via CYP3A4 induction.DailyMed (U.S. National Library of Medicine)
  • Coumarin-type anticoagulants (warfarin)Significant increase in anticoagulant effect may occur; careful monitoring of prothrombin time required; contraindicated in risk-reduction use.DailyMed (U.S. National Library of Medicine)
  • Rifampin, aminoglutethimide (CYP3A4 inducers)Reduce plasma tamoxifen and N-desmethyl tamoxifen concentrations via CYP3A4 induction.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعةPregnancy & breastfeeding
  • May cause fetal harm; women should not become pregnant during therapy or within 2 months after stopping and should use barrier or non-hormonal contraception.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • Tamoxifen inhibits early postpartum lactation; no data on excretion into human milk; neonatal animal exposure caused reproductive tract lesions.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
  • May cause fetal harm; women should not become pregnant during therapy or within 2 months after stopping and should use barrier or non-hormonal contraception.International label, same formulation · DailyMed (U.S. National Library of Medicine)
  • Tamoxifen inhibits early postpartum lactation; no data on excretion into human milk; neonatal animal exposure caused reproductive tract lesions.International label, same formulation · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواءHow it works
  • Nonsteroidal antiestrogen that competes with estrogen for binding at estrogen receptors (US label clinical pharmacology).
  • Tamoxifen: Nonsteroidal antiestrogen that competes with estrogen for binding at estrogen receptors (US label clinical pharmacology).

المثائل (2)

كل المثائل والبدائل

نفس المادة الفعالة والتركيز. اسأل الصيدلي قبل الاستبدال.

مثائل تاموكسيفين اكديما 10مجم 30 اقراص بنفس المادة الفعالة والتركيز، مرتبة من الأرخص
تاموكسيفين 10مجم 30 قرصTamoxifen 10mg 30 tabletsTechnopharm · قرص · Tamoxifen 10 mg per tabletالأرخصالسعر66ج.م2.2ج.م للوحدةالفرق عن الأصليأغلى 47.5ج.م (256.8%)
تاموفين10مجم 30 قرصTamofen 10mg 30 tabقرص · Tamoxifen 10 mg per tabletالسعر—الفرق عن الأصلي—

المعرّفات

الباركود
6224008302407
مراجع علمية للمادة الفعالة

أدوية ذات صلة

نفس المادة الفعالة بتركيز آخر

من فئة مضاد للأورام

المصادر

تعليقات

لا توجد تعليقات بعد. كن أول من يشارك تجربته مع هذا الدواء.

أضف تعليقًا

0/60

لا يُنشر أبدًا؛ للتواصل فقط إن لزم.

0/1000

من 20 إلى 1000 حرف. بدون روابط.

التعليقات للمعلومات العامة ولا تُعد نصيحة طبية. لا تذكر بيانات شخصية.