تخطَّ إلى المحتوى
دليل الأدوية المصري
تابع آخر تحديثات الأسعار على واتساب

سعر تاموكسيفين 40مجم 20 اقراص 2022

Tamoxifen 40mg 20 tab

معلومات الدواء

التفاصيل الكاملة
دواعي الاستعمالUses
  • Treatment of metastatic breast cancer in women and men; in premenopausal women an alternative to oophorectomy or ovarian irradiation (benefit more likely in estrogen-receptor-positive tumours).الفئة: AdultsDailyMed (U.S. National Library of Medicine)
  • Adjuvant treatment of node-positive and axillary node-negative breast cancer following surgery and radiation.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
  • Reduction of the risk of invasive breast cancer in women with ductal carcinoma in situ (DCIS) after surgery and radiation, and in women at high risk of breast cancer.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
  • Treatment of metastatic breast cancer in women and men; in premenopausal women an alternative to oophorectomy or ovarian irradiation (benefit more likely in estrogen-receptor-positive tumours).Population: AdultsDailyMed (U.S. National Library of Medicine)
  • Adjuvant treatment of node-positive and axillary node-negative breast cancer following surgery and radiation.Population: AdultsDailyMed (U.S. National Library of Medicine)
  • Reduction of the risk of invasive breast cancer in women with ductal carcinoma in situ (DCIS) after surgery and radiation, and in women at high risk of breast cancer.Population: AdultsDailyMed (U.S. National Library of Medicine)
الآثار الجانبيةSide effects
  • Most frequent adverse reaction in metastatic breast cancer is hot flashes; others include hypercalcaemia, peripheral oedema, distaste for food, pruritus vulvae, depression, dizziness, light-headedness, headache, hair thinning and vaginal dryness.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Most frequent adverse reaction in metastatic breast cancer is hot flashes; others include hypercalcaemia, peripheral oedema, distaste for food, pruritus vulvae, depression, dizziness, light-headedness, headache, hair thinning and vaginal dryness.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
موانع الاستعمالContraindications
  • Known hypersensitivity to tamoxifen or any ingredient.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • In risk-reduction settings (high-risk women and DCIS): women requiring concomitant coumarin-type anticoagulant therapy or with a history of deep vein thrombosis or pulmonary embolism.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Known hypersensitivity to tamoxifen or any ingredient.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
  • In risk-reduction settings (high-risk women and DCIS): women requiring concomitant coumarin-type anticoagulant therapy or with a history of deep vein thrombosis or pulmonary embolism.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطاتWarnings & precautions
  • Boxed warning: uterine malignancies (endometrial adenocarcinoma and uterine sarcoma), stroke and pulmonary embolism, some fatal, reported in the risk-reduction setting; benefits should be weighed against risks.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Hypercalcaemia may occur in patients with bone metastases within weeks of starting therapy; discontinue if severe.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Thromboembolic events (deep vein thrombosis, pulmonary embolism), cataracts and liver abnormalities are described in the label warnings.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Boxed warning: uterine malignancies (endometrial adenocarcinoma and uterine sarcoma), stroke and pulmonary embolism, some fatal, reported in the risk-reduction setting; benefits should be weighed against risks.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
  • Hypercalcaemia may occur in patients with bone metastases within weeks of starting therapy; discontinue if severe.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
  • Thromboembolic events (deep vein thrombosis, pulmonary embolism), cataracts and liver abnormalities are described in the label warnings.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائيةDrug interactions
  • Coumarin-type anticoagulants (warfarin)Significant increase in anticoagulant effect may occur; careful monitoring of prothrombin time required; contraindicated in risk-reduction use.DailyMed (U.S. National Library of Medicine)
  • Rifampin, aminoglutethimide (CYP3A4 inducers)Reduce plasma tamoxifen and N-desmethyl tamoxifen concentrations via CYP3A4 induction.DailyMed (U.S. National Library of Medicine)
  • Coumarin-type anticoagulants (warfarin)Significant increase in anticoagulant effect may occur; careful monitoring of prothrombin time required; contraindicated in risk-reduction use.DailyMed (U.S. National Library of Medicine)
  • Rifampin, aminoglutethimide (CYP3A4 inducers)Reduce plasma tamoxifen and N-desmethyl tamoxifen concentrations via CYP3A4 induction.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعةPregnancy & breastfeeding
  • May cause fetal harm; women should not become pregnant during therapy or within 2 months after stopping and should use barrier or non-hormonal contraception.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Tamoxifen inhibits early postpartum lactation; no data on excretion into human milk; neonatal animal exposure caused reproductive tract lesions.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • May cause fetal harm; women should not become pregnant during therapy or within 2 months after stopping and should use barrier or non-hormonal contraception.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
  • Tamoxifen inhibits early postpartum lactation; no data on excretion into human milk; neonatal animal exposure caused reproductive tract lesions.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواءHow it works
  • Nonsteroidal antiestrogen that competes with estrogen for binding at estrogen receptors (US label clinical pharmacology).
  • Tamoxifen: Nonsteroidal antiestrogen that competes with estrogen for binding at estrogen receptors (US label clinical pharmacology).

المعرّفات

مراجع علمية للمادة الفعالة

أدوية ذات صلة

نفس المادة الفعالة بتركيز آخر

منتجات أخرى من Amriya

من فئة مضاد للأورام

المصادر

تعليقات

لا توجد تعليقات بعد. كن أول من يشارك تجربته مع هذا الدواء.

أضف تعليقًا

0/60

لا يُنشر أبدًا؛ للتواصل فقط إن لزم.

0/1000

من 20 إلى 1000 حرف. بدون روابط.

التعليقات للمعلومات العامة ولا تُعد نصيحة طبية. لا تذكر بيانات شخصية.