سعر تافونيزا 10مجم 20 قرص 2025

Vonoprazan 10 mg film-coated tablets (potassium-competitive acid blocker), pack of 20 (2 strips), by ATCO Pharma (Egypt).

• Healing and maintenance of healing of erosive esophagitis with relief of heartburn; relief of heartburn in non-erosive GERD; H. pylori eradication in combination with antibacterials (adults).DailyMed (US National Library of Medicine)

• Most common in erosive esophagitis healing (>=2%): gastritis, diarrhea, abdominal distension, abdominal pain and nausea.International label, same formulation · DailyMed (US National Library of Medicine)

• Known hypersensitivity to vonoprazan or any component (anaphylactic shock reported); co-administration with rilpivirine-containing products.International label, same formulation · DailyMed (US National Library of Medicine)

• Symptomatic response does not exclude gastric malignancy; acute tubulointerstitial nephritis; C. difficile-associated diarrhea; bone fracture with long-term use; severe cutaneous adverse reactions (SJS/TEN); vitamin B12 deficiency; hypomagnesemia; false-positive chromogranin A tests; fundic gland polyps.International label, same formulation · DailyMed (US National Library of Medicine)

• Rilpivirine-containing productsContraindicated: reduced gastric acidity may lower rilpivirine exposure.DailyMed (US National Library of Medicine)

• No adequate well-controlled studies in pregnant women; available pharmacovigilance data are insufficient to establish drug-associated risk.International label, same formulation · DailyMed (US National Library of Medicine)
• Vonoprazan is present in human milk at less than 0.03% of the maternal dose; no data on effects on the breastfed child or milk production.International label, same formulation · DailyMed (US National Library of Medicine)

• Vonoprazan: Inhibits gastric H+/K+-ATPase in parietal cells without needing acid activation (directory pharmacology summary).