دواعي استعمال تينيدون 50/25مجم 30 قرص

Fixed-dose combination of atenolol (beta1-selective blocker) and chlorthalidone (thiazide-like diuretic) film-coated tablets marketed in Egypt by Sigma.

• Treatment of hypertension, to lower blood pressure.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Usually well tolerated; adverse effects are mostly mild and transient and essentially the same as those of the individual components (atenolol and chlorthalidone).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Sinus bradycardia, heart block greater than first degree, cardiogenic shock, overt cardiac failure, anuria, and hypersensitivity to the product or to sulfonamide-derived drugs.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Cardiac failure: beta blockade may depress myocardial contractility and precipitate more severe failure; withdraw if failure persists despite treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Use with caution in impaired renal function (thiazides may precipitate azotemia) and in hepatic impairment (fluid/electrolyte shifts may precipitate hepatic coma).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Calcium channel blockersMay have an additive effect when given with atenolol/chlorthalidone.DailyMed (U.S. National Library of Medicine)
• Catecholamine depletors (e.g., reserpine)Observe closely for hypotension and/or marked bradycardia.DailyMed (U.S. National Library of Medicine)
• LithiumDiuretics reduce lithium renal clearance and add a high risk of lithium toxicity; generally should not be co-administered.DailyMed (U.S. National Library of Medicine)
• ClonidineBeta-blockers may exacerbate rebound hypertension after clonidine withdrawal.DailyMed (U.S. National Library of Medicine)
• Prostaglandin synthase inhibitors (e.g., indomethacin)May decrease the hypotensive effect of beta-blockers.DailyMed (U.S. National Library of Medicine)

• Atenolol can cause fetal harm; use starting in the second trimester has been associated with infants small for gestational age; first-trimester fetal injury cannot be excluded.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Atenolol is excreted in breast milk (milk:plasma 1.5-6.8); clinically significant bradycardia reported in breastfed infants; neonates may be at risk of hypoglycemia and bradycardia.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• أتينولول: حاصر انتقائي لمستقبلات بيتا 1 الأدرينالية دون نشاط مثبت للأغشية أو نشاط محاكٍ ذاتي للودي؛ والانتقائية ليست مطلقة عند الجرعات الأعلى (النشرة الأمريكية).حاصر بيتا انتقائي لمستقبلات بيتا 1 (انتقائي للقلب)
• كلورتاليدون: مدر للبول شبيه بالثيازيد (سلفوناميدي)