سعر Thiotacid Compound 600 mg 2026
دواعي استعمال Thiotacid Compound
- Symptomatic diabetic peripheral neuropathy (evidence from IV and oral trials; approved for this use in Germany per LPI)الفئة: Adults with diabetesLinus Pauling Institute, Oregon State University
- Symptomatic diabetic peripheral neuropathy (evidence from IV and oral trials; approved for this use in Germany per LPI)Population: Adults with diabetesLinus Pauling Institute, Oregon State University
معلومات الدواء
التفاصيل الكاملةعن الدواءAbout the medicine
Thiotacid Compound 600 mg: oral film-coated caplets combining thioctic (alpha-lipoic) acid 600 mg with vitamin B1 and vitamin B12, by EVA Pharma (Egypt).
Thiotacid Compound 600 mg: oral film-coated caplets combining thioctic (alpha-lipoic) acid 600 mg with vitamin B1 and vitamin B12, by EVA Pharma (Egypt).
الآثار الجانبيةSide effects
- Most frequently reported side effects of oral lipoic acid are allergic skin reactions (rash, hives, itching); abdominal pain, nausea, vomiting, diarrhoea and vertigo have also been reported, with nausea, vomiting and vertigo dose-dependent in one trial.معلومة عامة عن المادة الفعالة · Linus Pauling Institute, Oregon State University
- Malodorous urine has been noted with oral lipoic acid 1,200 mg/day.معلومة عامة عن المادة الفعالة · Linus Pauling Institute, Oregon State University
- Most frequently reported side effects of oral lipoic acid are allergic skin reactions (rash, hives, itching); abdominal pain, nausea, vomiting, diarrhoea and vertigo have also been reported, with nausea, vomiting and vertigo dose-dependent in one trial.General active-ingredient information · Linus Pauling Institute, Oregon State University
- Malodorous urine has been noted with oral lipoic acid 1,200 mg/day.General active-ingredient information · Linus Pauling Institute, Oregon State University
تحذيرات واحتياطاتWarnings & precautions
- Accidental ingestion of four 600 mg tablets by a 20-month-old child caused seizures, acidosis and unconsciousness; a fatal non-accidental overdose in an adolescent has been reported. Keep out of reach of children.معلومة عامة عن المادة الفعالة · Linus Pauling Institute, Oregon State University
- Rare anaphylactoid/anaphylactic reactions have been reported after intravenous lipoic acid.معلومة عامة عن المادة الفعالة · Linus Pauling Institute, Oregon State University
- Use with caution under medical supervision in pregnancy/breastfeeding and in diabetes (insulin/antidiabetic dose adjustment) (retailer product text).حسب الشركة المنتجة
- Accidental ingestion of four 600 mg tablets by a 20-month-old child caused seizures, acidosis and unconsciousness; a fatal non-accidental overdose in an adolescent has been reported. Keep out of reach of children.General active-ingredient information · Linus Pauling Institute, Oregon State University
- Rare anaphylactoid/anaphylactic reactions have been reported after intravenous lipoic acid.General active-ingredient information · Linus Pauling Institute, Oregon State University
- Use with caution under medical supervision in pregnancy/breastfeeding and in diabetes (insulin/antidiabetic dose adjustment) (retailer product text).Per the manufacturer
التداخلات الدوائيةDrug interactions
- Insulin and oral antidiabetic agentsPossible additive hypoglycaemia; monitor blood glucose. A single-dose study found no significant interaction with glyburide or acarbose.Linus Pauling Institute, Oregon State University
- BiotinStructural similarity; high lipoic acid concentrations may compete with biotin for membrane transport (clinical relevance in humans unknown).Linus Pauling Institute, Oregon State University
- Insulin and oral antidiabetic agentsPossible additive hypoglycaemia; monitor blood glucose. A single-dose study found no significant interaction with glyburide or acarbose.Linus Pauling Institute, Oregon State University
- BiotinStructural similarity; high lipoic acid concentrations may compete with biotin for membrane transport (clinical relevance in humans unknown).Linus Pauling Institute, Oregon State University
الحمل والرضاعةPregnancy & breastfeeding
- Limited retrospective observational data (600 mg/day oral) showed no adverse effects in mothers or newborns; in the absence of further evidence, use in pregnancy only under strict medical supervision.معلومة عامة عن المادة الفعالة · Linus Pauling Institute, Oregon State University
- Safety of lipoic acid supplements during lactation has not been established; use should be discouraged.معلومة عامة عن المادة الفعالة · Linus Pauling Institute, Oregon State University
- Limited retrospective observational data (600 mg/day oral) showed no adverse effects in mothers or newborns; in the absence of further evidence, use in pregnancy only under strict medical supervision.General active-ingredient information · Linus Pauling Institute, Oregon State University
- Safety of lipoic acid supplements during lactation has not been established; use should be discouraged.General active-ingredient information · Linus Pauling Institute, Oregon State University
كيف يعمل الدواءHow it works
- حمض الثيوكتيك (حمض ألفا ليبويك): Protein-bound R-lipoic acid is a cofactor of mitochondrial dehydrogenase complexes; free lipoic acid and dihydrolipoic acid act as antioxidants and may enhance cellular glucose uptake (Linus Pauling Institute).مضاد للأكسدة؛ عامل مساعد لإنزيمات الميتوكوندريا
- بنفوتيامين (مشتق فيتامين ب1): مشتق ذائب في الدهون من الثيامين (فيتامين ب1)
- فيتامين ب12 (سيانوكوبالامين): فيتامين ذائب في الماء (كوبالامين)
- Thioctic acid (alpha-lipoic acid): Protein-bound R-lipoic acid is a cofactor of mitochondrial dehydrogenase complexes; free lipoic acid and dihydrolipoic acid act as antioxidants and may enhance cellular glucose uptake (Linus Pauling Institute).
- Benfotiamine (vitamin B1 derivative):
- Vitamin B12 (cyanocobalamin):
تابع أسعار الأدوية أول بأول
بننشر كل يوم أسعار أدوية اتغيرت والبدائل الأرخص
المعرّفات
- مراجع علمية للمادة الفعالة
- Thioctic acid (alpha-lipoic acid)PubChem (يفتح في نافذة جديدة)
أدوية ذات صلة
نفس المادة الفعالة بتركيز آخر
منتجات أخرى من EVA Pharma
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- Linus Pauling Institute, Oregon State University
- PubChem (NCBI)
تعليقات
لا توجد تعليقات بعد. كن أول من يشارك تجربته مع هذا الدواء.
أضف تعليقًا