سعر تيكالوجارد Ticaloguard‏ 90مجم 30 قرص 2026

Ticagrelor 90 mg film-coated tablets (Marcyrl, Egypt), reversible P2Y12 antiplatelet.

• Most common (>5%): bleeding and dyspnoea.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of intracranial haemorrhage; active pathological bleeding (e.g. peptic ulcer, intracranial haemorrhage); hypersensitivity (e.g. angioedema) to ticagrelor.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: can cause significant, sometimes fatal bleeding. Do not start in patients undergoing urgent CABG; if possible manage bleeding without stopping, as stopping increases the risk of cardiovascular events.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Dyspnoea occurs more often than with comparators and is self-limiting; severe hepatic impairment likely increases exposure; false-negative platelet functional tests for HIT have been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A inhibitors (e.g. ketoconazole, itraconazole, clarithromycin, ritonavir)Avoid: substantially increase ticagrelor exposure and risk of bleeding and dyspnoea.DailyMed (U.S. National Library of Medicine)
• Strong CYP3A inducers (e.g. rifampin, phenytoin, carbamazepine, phenobarbital)Avoid: substantially reduce ticagrelor exposure and efficacy.DailyMed (U.S. National Library of Medicine)
• OpioidsDecreased ticagrelor exposure; consider a parenteral antiplatelet agent.DailyMed (U.S. National Library of Medicine)

• Case-report data have not identified a drug-associated risk of major birth defects or miscarriage; animal studies showed structural abnormalities at ~5-7 times the maximum recommended human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No human milk data; present in rat milk. Breastfeeding is not recommended during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)