سعر تولمتيرودين Tolterodine‏ 4مجم 10 اقراص 2026

Tolterodine L-tartrate 4 mg extended-release capsules (Sabaa/Activa Therapeutics, Egypt), antimuscarinic for overactive bladder; pack of 10.

• Most common: dry mouth, headache, constipation and abdominal pain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Urinary retention, gastric retention or uncontrolled narrow-angle glaucoma; hypersensitivity to tolterodine, its ingredients or to fesoterodine fumarate (both metabolised to 5-hydroxymethyl tolterodine).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anaphylaxis and angioedema requiring hospitalisation have occurred; discontinue if breathing difficulty, upper airway obstruction or hypotension occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Anticholinergic CNS effects may occur; monitor particularly after starting treatment or increasing the dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potent CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, ritonavir)Recommended dose is 2 mg once daily with potent CYP3A4 inhibitors.DailyMed (U.S. National Library of Medicine)

• No available data in pregnant women to inform drug-associated risk; adverse developmental outcomes in mice only at doses above about 9-12 times clinical exposure.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No information on presence in human milk; consider breastfeeding benefits with the mother's clinical need and potential infant effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Tolterodine L-tartrate: Competitive antagonist of acetylcholine at postganglionic muscarinic receptors; active metabolite 5-hydroxymethyl tolterodine contributes to the effect.