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معلومات الدواء

تحذيرات واحتياطاتWarnings & precautions
  • Theophylline has a narrow therapeutic range; many conditions (extremes of age, heart failure, fever, liver disease) and drugs reduce its clearance; serious adverse effects become more likely above serum concentrations of 20 mcg/mL.معلومة عامة عن المادة الفعالة
  • Diphenhydramine: do not use with other diphenhydramine-containing products; ask a doctor first with glaucoma, breathing problems or an enlarged prostate.معلومة عامة عن المادة الفعالة
  • Guaifenesin: ask a doctor first with persistent or chronic cough (smoking, asthma, chronic bronchitis, emphysema) or cough with excessive phlegm.معلومة عامة عن المادة الفعالة
  • Theophylline has a narrow therapeutic range; many conditions (extremes of age, heart failure, fever, liver disease) and drugs reduce its clearance; serious adverse effects become more likely above serum concentrations of 20 mcg/mL.General active-ingredient information
  • Diphenhydramine: do not use with other diphenhydramine-containing products; ask a doctor first with glaucoma, breathing problems or an enlarged prostate.General active-ingredient information
  • Guaifenesin: ask a doctor first with persistent or chronic cough (smoking, asthma, chronic bronchitis, emphysema) or cough with excessive phlegm.General active-ingredient information
التداخلات الدوائيةDrug interactions
  • Theophylline metabolism inhibitors (e.g. cimetidine, erythromycin)Raise theophylline levels; toxicity risk.
  • Metabolism inducers (e.g. carbamazepine, rifampin)Lower theophylline levels; stopping them raises levels.
  • Theophylline metabolism inhibitors (e.g. cimetidine, erythromycin)Raise theophylline levels; toxicity risk.
  • Metabolism inducers (e.g. carbamazepine, rifampin)Lower theophylline levels; stopping them raises levels.
الحمل والرضاعةPregnancy & breastfeeding
  • Theophylline is excreted into breast milk at about the maternal serum concentration and may cause irritability or mild toxicity in the infant.معلومة عامة عن المادة الفعالة
  • Theophylline is excreted into breast milk at about the maternal serum concentration and may cause irritability or mild toxicity in the infant.General active-ingredient information
كيف يعمل الدواءHow it works
  • ديفينهيدرامين: Competitive H1-receptor antagonism; central antitussive effects.
  • جوايفينيسين: May irritate gastric vagal receptors recruiting parasympathetic reflexes that increase less-viscous respiratory secretions.مذيب بلغم
  • ثيوفيلين: Relaxes airway smooth muscle (bronchodilation) and suppresses airway responsiveness to stimuli; bronchodilation is thought to be mediated by inhibition of phosphodiesterase isozymes PDE III and, to a lesser extent, PDE IV (US label; mechanisms not known with certainty).ميثيل زانثين (مثبط فوسفوديستراز)
  • Diphenhydramine: Competitive H1-receptor antagonism; central antitussive effects.
  • Guaifenesin: May irritate gastric vagal receptors recruiting parasympathetic reflexes that increase less-viscous respiratory secretions.
  • Theophylline: Relaxes airway smooth muscle (bronchodilation) and suppresses airway responsiveness to stimuli; bronchodilation is thought to be mediated by inhibition of phosphodiesterase isozymes PDE III and, to a lesser extent, PDE IV (US label; mechanisms not known with certainty).

تابع أسعار الأدوية أول بأول

بننشر كل يوم أسعار أدوية اتغيرت والبدائل الأرخص

المعرّفات

المصادر

  • السعر: قوائم أسعار الأدوية المنشورة في مصر.

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