سعر توينستا Twynsta‏ 80/10مجم 28 اقراص 2026

Twynsta 80/10 mg tablets (telmisartan 80 mg + amlodipine 10 mg), pack of 28, Boehringer Ingelheim.

• Most common: peripheral oedema, dizziness, clinically significant hypotension and back pain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity (e.g. anaphylaxis or angioedema) to telmisartan, amlodipine or any component; do not co-administer aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING - fetal toxicity: discontinue as soon as pregnancy is detected; drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus. Also: hypotension in volume/salt-depleted patients, hyperkalaemia, impaired renal function, titrate slowly in hepatic impairment, possible worsening angina/MI on starting a calcium channel blocker.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Aliskiren / ACE inhibitors (dual RAS blockade)Increased risk of hypotension, hyperkalaemia and renal function changes; avoid aliskiren in diabetes.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium concentrations and toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay cause deterioration of renal function and attenuate the antihypertensive effect.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm; use in the 2nd and 3rd trimesters reduces fetal renal function and increases fetal/neonatal morbidity and death. Discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No information on telmisartan in human milk; limited published studies report amlodipine is present in human milk with insufficient information on effects on the breastfed infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)