سعر اولميدبين 5مجم/40مجم 20 اقراص 2022

Olmedipine film-coated tablets (amlodipine 5 mg + olmesartan 40 mg) by Bioxell Pharma for hypertension; 20 tablets per pack.

• Treatment of hypertension, to lower blood pressure.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reaction (incidence >=3%) is oedema.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Do not co-administer aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Fetal toxicity: drugs acting on the renin-angiotensin system during the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Correct volume or salt depletion before starting (risk of symptomatic hypotension); monitor renal function and potassium in susceptible patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Increased angina or myocardial infarction may occur on starting or increasing the dose (amlodipine component).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• LithiumIncreased serum lithium concentrations and toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay deteriorate renal function and attenuate the antihypertensive effect.DailyMed (U.S. National Library of Medicine)
• ColesevelamReduces olmesartan exposure; give olmesartan at least 4 hours before colesevelam.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm; discontinue as soon as possible when pregnancy is detected (RAS-acting component).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Amlodipine: Inhibits calcium influx into vascular smooth muscle, causing peripheral arterial vasodilation.
• Olmesartan: Olmesartan medoxomil is a prodrug hydrolysed to olmesartan, which blocks angiotensin II at the AT1 receptor.