سعر تيجاسيل Tygacil‏ 50مجم حقنة وريد فيال 2026

Tygacil (tigecycline) 50 mg lyophilised powder for intravenous infusion, single vial, Pfizer.

• Most common: nausea and vomiting, diarrhoea, infection, increased ALT/AST, abdominal pain.International label, same product · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to tigecycline.International label, same product · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING - all-cause mortality: increased all-cause mortality vs comparators in clinical trials; reserve for situations where alternative treatments are not suitable. Also: anaphylaxis, hepatotoxicity, pancreatitis, hypofibrinogenaemia/coagulopathy (monitor fibrinogen), tooth discoloration and enamel hypoplasia if used during tooth development (pregnancy, children <8 years), C. difficile-associated diarrhoea.International label, same product · DailyMed (U.S. National Library of Medicine)

• WarfarinMonitor prothrombin time/INR when co-administered.DailyMed (U.S. National Library of Medicine)
• Calcineurin inhibitors (tacrolimus, cyclosporine)May increase their trough concentrations; monitor levels.DailyMed (U.S. National Library of Medicine)
• Oral contraceptivesConcurrent antibacterial use may render oral contraceptives less effective.DailyMed (U.S. National Library of Medicine)

• May cause fetal harm; use during the second and third trimesters can cause permanent tooth discoloration and reversible inhibition of bone growth in the fetus.International label, same product · DailyMed (U.S. National Library of Medicine)
• No data on tigecycline in human milk (tetracycline-class drugs are present in breast milk); low oral bioavailability so infant exposure expected to be low; weigh benefits of breastfeeding against the mother's need for the drug.International label, same product · DailyMed (U.S. National Library of Medicine)