سعر امفلوكس amflux‏ 500مجم فيال 2026

Amoxicillin + flucloxacillin 500 mg vial powder for injection (Pharco).

• Amoxicillin: diarrhoea, nausea and skin rash are most common; rare severe allergic reactions, haematological changes, crystalluria with high IV doses.General active-ingredient information · electronic medicines compendium (emc)
• Flucloxacillin: very rare neutropenia, thrombocytopenia, anaphylaxis, hepatitis/cholestatic jaundice; high (mainly parenteral) doses may cause neurotoxicity.General active-ingredient information · electronic medicines compendium (emc)

• Amoxicillin: hypersensitivity to penicillins; history of severe immediate hypersensitivity (e.g. anaphylaxis) to another beta-lactam (cephalosporin, carbapenem or monobactam).General active-ingredient information · electronic medicines compendium (emc)
• Flucloxacillin: hypersensitivity to beta-lactams; previous flucloxacillin-associated jaundice/hepatic dysfunction.General active-ingredient information · electronic medicines compendium (emc)

• Serious and occasionally fatal hypersensitivity reactions (including anaphylactoid and severe cutaneous reactions) have occurred with penicillins; enquire about previous beta-lactam reactions before treatment.General active-ingredient information · electronic medicines compendium (emc)
• Flucloxacillin: hepatitis and cholestatic jaundice have been reported (not dose- or route-related); caution in hepatic dysfunction; AGEP possible; in severe renal failure (CrCl <10 mL/min) consider dose reduction (neurotoxicity risk).General active-ingredient information · electronic medicines compendium (emc)

• ProbenecidDecreases renal tubular secretion, increasing and prolonging amoxicillin and flucloxacillin levels; not recommended with amoxicillin.electronic medicines compendium (emc)
• Warfarin / oral anticoagulantsAltered INR reported; monitor INR when starting or stopping the antibiotic.electronic medicines compendium (emc)
• MethotrexatePenicillins reduce methotrexate excretion; risk of methotrexate toxicity.electronic medicines compendium (emc)
• AllopurinolIncreased likelihood of allergic skin reactions with amoxicillin.electronic medicines compendium (emc)

• Amoxicillin: limited human data do not indicate an increased risk of malformations; may be used when benefits outweigh risks.General active-ingredient information · electronic medicines compendium (emc)
• Amoxicillin is excreted into breast milk in small quantities (risk of sensitisation, diarrhoea or candidiasis in the infant).General active-ingredient information · electronic medicines compendium (emc)

• Amoxicillin: Bactericidal beta-lactam that inhibits bacterial cell-wall biosynthesis during active multiplication; inactivated by beta-lactamases (US label, section 12.4).
• Flucloxacillin: Isoxazolyl penicillin of the beta-lactam group with bactericidal activity against many Gram-positive organisms, including beta-lactamase-producing staphylococci and streptococci (UK SmPC).