سعر يوريك بيور Uric pure‏ 300مجم 30 قرص 2026

Uric pure 300 mg tablets (Mepaco, Egypt): allopurinol 300 mg, a xanthine oxidase inhibitor that lowers uric acid; pack of 30 tablets.

• Most common (>=1%): diarrhea, nausea, increased alkaline phosphatase and AST/ALT, acute gout attacks, rash/maculopapular rash; skin rash is the most frequent.International label, same formulation · DailyMed (NLM)

• History of hypersensitivity to allopurinol or any tablet ingredient.International label, same formulation · DailyMed (NLM)

• Serious, sometimes fatal skin reactions (SJS, TEN, DRESS) in about 0.05% of patients; discontinue permanently at first rash or hypersensitivity sign; HLA-B*58:01 carriers are at higher risk.International label, same formulation · DailyMed (NLM)
• Gout flares on initiation (prophylactic colchicine/anti-inflammatory recommended); nephrotoxicity; reversible hepatotoxicity; bone marrow suppression; drowsiness/dizziness affecting driving.International label, same formulation · DailyMed (NLM)

• Mercaptopurine / azathioprineReduce mercaptopurine or azathioprine dose as recommended in their labels.DailyMed (NLM)
• CapecitabineAvoid concomitant use (may decrease capecitabine efficacy).DailyMed (NLM)
• PegloticaseDiscontinue and do not initiate allopurinol.DailyMed (NLM)

• Based on animal findings, allopurinol may cause fetal harm; allopurinol and oxypurinol cross the placenta; limited human data (about 50 pregnancies, 2 major malformations) show no clear pattern; advise of potential fetal risk.International label, same formulation · DailyMed (NLM)
• Allopurinol and oxypurinol are present in human milk; advise not to breastfeed during treatment and for one week after the last dose.International label, same formulation · DailyMed (NLM)

• Allopurinol: Inhibits xanthine oxidase (as does its metabolite oxypurinol), reducing the formation of uric acid.