سعر انجينيترا 5 مجم 10 اقراص 2022

Sublingual tablets containing isosorbide dinitrate 5 mg, an organic nitrate antianginal (Anginitra, Chemipharm, Egypt); 10 tablets per pack.

• Prophylaxis of ischaemic heart pain (angina) associated with coronary insufficiencyPopulation: AdultsHealth Canada Drug Product Database (DPD)

• Headache (may be severe; usually subsides within about a week), dizziness, postural hypotension, flushing.International label, same formulation · Health Canada Drug Product Database (DPD)
• Occasionally drug rash or exfoliative dermatitis; rarely methaemoglobinaemia.International label, same formulation · Health Canada Drug Product Database (DPD)

• Hypersensitivity to isosorbide dinitrate, other nitrates or any excipient.International label, same formulation · Health Canada Drug Product Database (DPD)
• Concomitant use of phosphodiesterase-5 inhibitors (sildenafil, tadalafil, vardenafil) or the guanylate cyclase stimulator riociguat.International label, same formulation · Health Canada Drug Product Database (DPD)

• Not recommended in early acute myocardial infarction or congestive heart failure without close haemodynamic monitoring.International label, same formulation · Health Canada Drug Product Database (DPD)
• Severe hypotension (with paradoxical bradycardia and increased angina) may occur; caution in volume depletion, hypotension, hypertrophic obstructive cardiomyopathy.International label, same formulation · Health Canada Drug Product Database (DPD)
• Tolerance and cross-tolerance to nitrates; abrupt withdrawal may precipitate angina.International label, same formulation · Health Canada Drug Product Database (DPD)

• PDE-5 inhibitors (sildenafil, tadalafil, vardenafil)Marked potentiation of hypotension - contraindicated.Health Canada Drug Product Database (DPD)
• RiociguatAdditive hypotension - contraindicated.Health Canada Drug Product Database (DPD)
• Alcohol and other blood-pressure-lowering drugs (antihypertensives, vasodilators)Additive hypotensive effect.Health Canada Drug Product Database (DPD)

• Embryotoxicity was seen in rabbits at high doses; there are no adequate studies in pregnant women - use only if the potential benefit justifies the potential risk.International label, same formulation · Health Canada Drug Product Database (DPD)
• Excretion in human milk is unknown; use with caution in nursing women.International label, same formulation · Health Canada Drug Product Database (DPD)

• Isosorbide dinitrate: Relaxes vascular smooth muscle, venous more than arterial, reducing venous return (preload) and to a lesser extent arterial resistance (afterload), lowering myocardial oxygen demand.