سعر ايزوربيد 5 مجم 100 مجم 2022

Isorbid isosorbide dinitrate 5 mg sublingual tablets, pack of 100, for prophylaxis of angina.

• Prophylaxis of ischemic heart pain associated with coronary insufficiency; may reduce the number, duration and severity of anginal attacks and nitroglycerin requirements.Population: AdultsHealth Canada Drug Product Database (DPD)

• Hypersensitivity to isosorbide dinitrate or any ingredient; concomitant use of PDE5 inhibitors (e.g. sildenafil, tadalafil, vardenafil) or the soluble guanylate cyclase stimulator riociguat; withhold in cardiogenic shock or if there is a risk of shock after myocardial infarction.International label, same formulation · Health Canada Drug Product Database (DPD)

• Nitrate tolerance may develop with continuous plasma levels; a daily dose-free interval is advisable. Severe hypotension (especially upright) may occur; alcohol may worsen postural hypotension.International label, same formulation · Health Canada Drug Product Database (DPD)

• At high multiples of the human dose, isosorbide dinitrate caused a dose-related increase in embryotoxicity in rabbits; no adequate studies in pregnant women; use only if the potential benefit justifies the potential risk to the fetus.International label, same formulation · Health Canada Drug Product Database (DPD)
• Unknown whether isosorbide dinitrate is excreted in human milk; caution.International label, same formulation · Health Canada Drug Product Database (DPD)

• Isosorbide dinitrate: Relaxes vascular smooth muscle, predominantly veins, reducing preload and myocardial oxygen demand.