سعر اريميدكس 1مجم 28 قرص 2024

Arimidex 1 mg tablets (anastrozole 1 mg), a non-steroidal aromatase inhibitor for hormone receptor-positive breast cancer in postmenopausal women, marketed in Egypt by AstraZeneca; pack of 28 tablets (2 strips).

• Treatment of hormone receptor-positive advanced breast cancerPopulation: Postmenopausal womenelectronic medicines compendium (emc), UK
• Adjuvant treatment of hormone receptor-positive early invasive breast cancer (including after 2-3 years of adjuvant tamoxifen)Population: Postmenopausal womenelectronic medicines compendium (emc), UK
• Primary prevention of breast cancer in women at moderate or high riskPopulation: Postmenopausal womenelectronic medicines compendium (emc), UK

• Most common (>=10%) in women taking ARIMIDEX in the adjuvant ATAC trial: hot flashes, asthenia, arthritis, pain, arthralgia, hypertension, depression, nausea and vomiting, rash, osteoporosis, fractures, back pain, insomnia, headache, bone pain, peripheral edema, increased cough, dyspnea, pharyngitis and lymphedema.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Pregnant or breastfeeding women.International label, same formulation · electronic medicines compendium (emc), UK
• Known hypersensitivity to anastrozole or to any of the excipients.International label, same formulation · electronic medicines compendium (emc), UK
• Hypersensitivity reactions to the drug or excipients (observed: anaphylaxis, angioedema, urticaria).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Should not be used in premenopausal women; confirm menopause biochemically (LH, FSH and/or estradiol) where in doubt; no data with LHRH analogues.International label, same formulation · electronic medicines compendium (emc), UK
• Lowers circulating estrogen and may reduce bone mineral density with increased fracture risk; assess BMD at the start in women with or at risk of osteoporosis.International label, same formulation · electronic medicines compendium (emc), UK
• In the IBIS-II prevention study, hypertension, hypercholesterolaemia and cardiovascular events were more frequent with anastrozole than placebo; consider these risks.International label, same formulation · electronic medicines compendium (emc), UK

• TamoxifenDo not co-administer: tamoxifen reduced anastrozole plasma concentrations by 27% and the combination showed no efficacy benefit over tamoxifen alone.DailyMed (U.S. National Library of Medicine)
• Estrogen-containing therapiesMay diminish the pharmacological action of anastrozole; do not use together.DailyMed (U.S. National Library of Medicine)

• Based on animal findings and its mechanism, anastrozole can cause fetal harm; verify pregnancy status before starting and use effective contraception during treatment and for at least 3 weeks after the last dose.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• No data in pregnant women; animal studies showed reproductive toxicity; Arimidex is contraindicated during pregnancy.International label, same formulation · electronic medicines compendium (emc), UK
• No data on presence in human milk; advise not to breastfeed during treatment and for 2 weeks after the last dose.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Anastrozole: Selective non-steroidal aromatase inhibitor: blocks conversion of adrenal androgens to estrone and estradiol, lowering estrogen levels in postmenopausal women.