سعر ارتفارمادينت 100000-50 كارتريدجيس 1.7 مل Articaine HCl 4% 2024

Articaine hydrochloride 4% (68 mg per 1.7 ml cartridge) with epinephrine 1:100,000 (0.017 mg per cartridge) dental local anaesthetic, box of 50 cartridges x 1.7 ml, Art Pharma (Egypt).

• Local, infiltrative or conductive anaesthesia in both simple and complex dental procedures.Population: Adults and children 4 years of age and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>2%): headache and pain.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Post-marketing: persistent paraesthesia of lips, tongue and oral tissues (mainly after mandibular nerve blocks), ischaemic injury or necrosis at the injection site, and ocular muscle paralysis/visual disturbances.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to sulfite (the product contains sodium metabisulfite).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Accidental intravascular injection may cause cardiac arrhythmias or cardiac arrest; aspirate before injecting.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Systemic toxicity (CNS excitation or depression, cardiovascular depression) with high plasma levels; have resuscitation equipment and oxygen available.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Epinephrine-related cardiovascular reactions; use with caution in patients with ischaemic heart disease, cerebral vascular insufficiency, hypertension or peripheral vascular disease.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• MAO inhibitors, nonselective beta-adrenergic antagonists, tricyclic antidepressantsMay produce severe, prolonged hypertension with the epinephrine component.DailyMed (U.S. National Library of Medicine)
• Phenothiazines and butyrophenonesMay reduce or reverse the pressor effect of epinephrine.DailyMed (U.S. National Library of Medicine)
• Drugs associated with methemoglobinemia (e.g. nitrates/nitrites, other local anaesthetics, dapsone, sulfonamides, antimalarials)Increased risk of methemoglobinemia.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; in rabbits fetal deaths and skeletal variations occurred at about 4 times the maximum recommended human dose. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether articaine is excreted in human milk; nursing mothers may choose to pump and discard milk for about 4 hours after injection.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Articaine hydrochloride: Blocks the generation and conduction of nerve impulses by reducing sodium permeability of the nerve membrane (label).
• Epinephrine (adrenaline): Local vasoconstriction slows systemic absorption, prolonging and intensifying the anaesthetic effect (label).