سعر ازماكاست 10مجم 30 قرص 2024

Montelukast 10 mg film-coated tablets by Mina Pharm - Sandoz, a leukotriene receptor antagonist marketed in Egypt; pack of 30 tablets.

• Prophylaxis and chronic treatment of asthmaPopulation: Adults and pediatric patients 12 months and olderDailyMed (U.S. National Library of Medicine)
• Prevention of exercise-induced bronchoconstrictionPopulation: Patients 6 years and olderDailyMed (U.S. National Library of Medicine)
• Relief of symptoms of seasonal allergic rhinitis (when alternatives are inadequate or not tolerated)Population: Patients 2 years and olderDailyMed (U.S. National Library of Medicine)

• Most common (>=5% and more than placebo) across trials: upper respiratory infection, fever, headache, pharyngitis, cough, abdominal pain, diarrhoea, otitis media, influenza, rhinorrhoea, sinusitis and otitis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Adults and adolescents 15 years and older with asthma (10 mg tablet): headache (18.4%), influenza, abdominal pain, cough, dyspepsia and raised ALT/AST.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: serious neuropsychiatric events (agitation, depression, sleep disturbance, suicidal thoughts and behaviour) have been reported; for allergic rhinitis reserve for patients with inadequate response or intolerance to alternatives; discuss benefits and risks and advise stopping and contacting a prescriber if such changes occur.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Not for treatment of acute asthma attacks, including status asthmaticus; keep rescue medication available.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Do not abruptly substitute for inhaled or oral corticosteroids.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, warfarin, thyroid hormones, sedative hypnotics, NSAIDs, benzodiazepines, decongestants and CYP450 inducers (e.g. phenobarbital, rifampin)No dose adjustment of montelukast is needed when co-administered with these medicines at recommended doses.DailyMed (U.S. National Library of Medicine)

• Available data from published prospective and retrospective cohort studies over decades have not established a drug-associated risk of major birth defects; poorly or moderately controlled asthma in pregnancy itself increases maternal and fetal risks.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Montelukast is present in human milk; available data do not suggest significant infant risk; weigh the benefits of breastfeeding against the mother's clinical need.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Montelukast: Selective, orally active antagonist of the cysteinyl leukotriene CysLT1 receptor, blocking leukotriene D4-mediated airway oedema, smooth-muscle contraction and inflammation (US SINGULAIR label).