سعر ازمالير 5 مجم 10 اقراص 2022

Montelukast 5 mg tablets by Hi-Pharm, a leukotriene receptor antagonist marketed in Egypt; pack of 10 tablets.

• Most common (>=5% and more than placebo) across trials: upper respiratory infection, fever, headache, pharyngitis, cough, abdominal pain, diarrhoea, otitis media, influenza, rhinorrhoea, sinusitis and otitis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Adults and adolescents 15 years and older with asthma (10 mg tablet): headache (18.4%), influenza, abdominal pain, cough, dyspepsia and raised ALT/AST.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Boxed warning: serious neuropsychiatric events (agitation, depression, sleep disturbance, suicidal thoughts and behaviour) have been reported; for allergic rhinitis reserve for patients with inadequate response or intolerance to alternatives; discuss benefits and risks and advise stopping and contacting a prescriber if such changes occur.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Not for treatment of acute asthma attacks, including status asthmaticus; keep rescue medication available.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Do not abruptly substitute for inhaled or oral corticosteroids.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Patients with known aspirin sensitivity should continue avoiding aspirin and NSAIDs while taking montelukast.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Systemic eosinophilia, sometimes with features of vasculitis consistent with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome), has been reported, often associated with corticosteroid reduction.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, warfarin, thyroid hormones, sedative hypnotics, NSAIDs, benzodiazepines, decongestants and CYP450 inducers (e.g. phenobarbital, rifampin)No dose adjustment of montelukast is needed when co-administered with these medicines at recommended doses.DailyMed (U.S. National Library of Medicine)

• Available data from published prospective and retrospective cohort studies over decades have not established a drug-associated risk of major birth defects; poorly or moderately controlled asthma in pregnancy itself increases maternal and fetal risks.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Montelukast is present in human milk; available data do not suggest significant infant risk; weigh the benefits of breastfeeding against the mother's clinical need.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Montelukast: Selective, orally active antagonist of the cysteinyl leukotriene CysLT1 receptor, blocking leukotriene D4-mediated airway oedema, smooth-muscle contraction and inflammation (US SINGULAIR label).