سعر اتاراكس 25 مجم 25 قرص 2026

Hydroxyzine hydrochloride 25 mg tablets, 25 tablets; sedating H1-antihistamine (piperazine derivative) used for anxiety and pruritus (CID, Egypt).

• To assist in the management of anxiety.Population: Adultselectronic medicines compendium (eMC)
• Pruritus associated with acute and chronic urticaria (including cholinergic and physical types) and atopic and contact dermatitis.Population: Adults and childrenelectronic medicines compendium (eMC)

• Most common: CNS depression (drowsiness to deep sleep, lassitude, dizziness, incoordination), headache, psychomotor impairment and antimuscarinic effects; paradoxical stimulation may occur, especially at high doses and in children and the elderly.International label, same formulation · electronic medicines compendium (eMC)
• Frequency not known: QT prolongation, ventricular arrhythmias (torsade de pointes), tachycardia, hypotension, hypersensitivity/anaphylaxis/angioedema, blood disorders, liver dysfunction, dry mouth, constipation, urinary retention, blurred vision, convulsions (usually at high doses), AGEP, fixed drug eruption; very rare Stevens-Johnson syndrome and erythema multiforme.International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to hydroxyzine, cetirizine, other piperazine derivatives, aminophylline, ethylenediamine or any excipient.International label, same formulation · electronic medicines compendium (eMC)
• Known acquired or congenital QT prolongation, or known risk factors for QT prolongation (cardiovascular disease, hypokalaemia/hypomagnesaemia, family history of sudden cardiac death, significant bradycardia, concomitant QT-prolonging or torsade-inducing drugs).International label, same formulation · electronic medicines compendium (eMC)
• Asthmatics with a previous serious antihistamine-induced bronchopulmonary reaction; porphyria.International label, same formulation · electronic medicines compendium (eMC)

• QT prolongation and torsade de pointes have been reported (mostly with other risk factors); stop treatment if signs of arrhythmia occur and advise patients to report cardiac symptoms promptly.International label, same formulation · electronic medicines compendium (eMC)
• Use with caution in angle-closure glaucoma, urinary retention, prostatic hyperplasia, pyloroduodenal obstruction, seizure disorders, myasthenia gravis, dementia, decreased GI motility, breathing problems, hyperthyroidism, cardiovascular disease and hypertension.International label, same formulation · electronic medicines compendium (eMC)
• Avoid alcohol; may impair judgement, alertness and the ability to drive or operate machinery; children and the elderly are more susceptible to side effects.International label, same formulation · electronic medicines compendium (eMC)

• Drugs that prolong the QT interval or induce torsade de pointes (class IA/III antiarrhythmics, some antihistamines, antipsychotics, antidepressants such as citalopram/escitalopram, mefloquine, erythromycin, levofloxacin, moxifloxacin, pentamidine, prucalopride, methadone, toremifene, vandetanib)Increased risk of cardiac arrhythmia; combination contraindicated.electronic medicines compendium (eMC)
• Alcohol and CNS depressants (barbiturates, benzodiazepines, hypnotics, opioids, antipsychotics, antidepressants, other antihistamines, muscle relaxants, anaesthetics)Enhanced sedation; avoid alcohol and adjust doses.electronic medicines compendium (eMC)
• Antimuscarinic/anticholinergic drugs (e.g. atropine, tricyclic antidepressants, MAOIs)Additive antimuscarinic effects.electronic medicines compendium (eMC)

• Contraindicated in pregnancy: human data are inadequate to establish safety in early pregnancy; animal studies showed reproductive toxicity and hydroxyzine crosses the placenta.International label, same formulation · electronic medicines compendium (eMC)
• Contraindicated during breastfeeding; hydroxyzine is expected to be excreted in breast milk.International label, same formulation · electronic medicines compendium (eMC)

• Hydroxyzine hydrochloride: Piperazine-derivative H1-antihistamine with anxiolytic and sedative activity (suppression of subcortical CNS activity); its active metabolite is cetirizine.