سعر اتميبلاست 20مجم 30 قرص 2022

Bilastine 20 mg tablets, a second-generation (non-sedating) H1 antihistamine, listed in Egypt under EGPI / ATM Pharmaceutical Industries; pack of 30 tablets.

• Symptomatic treatment of allergic rhinoconjunctivitis (seasonal and perennial)Population: Adults and adolescents 12 years and olderelectronic medicines compendium (emc), UK
• Symptomatic treatment of urticariaPopulation: Adults and adolescents 12 years and olderelectronic medicines compendium (emc), UK

• Overall adverse event incidence with 20 mg was comparable to placebo (12.7% vs 12.8%); most commonly reported: headache, somnolence, dizziness and fatigue (similar frequency to placebo).International label, equivalent formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to bilastine or to any of the excipients.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Cases of QT prolongation have been reported; use with caution in patients at increased risk (history of arrhythmias, hypokalaemia, hypomagnesaemia, hypocalcaemia, known QT prolongation, significant bradycardia, other QT-prolonging drugs).International label, equivalent formulation · electronic medicines compendium (emc), UK
• In moderate or severe renal impairment avoid co-administration with P-glycoprotein inhibitors (e.g. ketoconazole, erythromycin, ciclosporin, ritonavir, diltiazem), which may raise bilastine levels.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Driving was not affected at 20 mg in a dedicated study, but patients should not drive or use machines until they know their own response.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Food, grapefruit juice and possibly other fruit juices; OATP1A2 substrates/inhibitors (e.g. ritonavir, rifampicin)Food and grapefruit juice decrease bilastine bioavailability by about 30%; OATP1A2 substrates or inhibitors may likewise decrease bilastine levels.electronic medicines compendium (emc), UK
• Ketoconazole, erythromycin, diltiazem and other P-glycoprotein substrates/inhibitors (e.g. ciclosporin)Ketoconazole or erythromycin increased bilastine AUC 2-fold and Cmax 2-3-fold; diltiazem increased Cmax by 50%; no apparent change in safety profile (avoid P-gp inhibitors in moderate/severe renal impairment).electronic medicines compendium (emc), UK
• Alcohol; lorazepamNo potentiation of psychomotor impairment by alcohol or of CNS-depressant effects of lorazepam was observed.electronic medicines compendium (emc), UK

• No or limited data in pregnant women; animal studies do not indicate harmful reproductive effects. As a precaution, it is preferable to avoid use during pregnancy.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Excretion in human milk has not been studied (excreted in animal milk); decide whether to continue breastfeeding or bilastine therapy weighing the benefits of each.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Bilastine: Non-sedating, long-acting antihistamine with selective peripheral H1-receptor antagonist affinity and no affinity for muscarinic receptors; inhibits histamine-induced wheal and flare for 24 hours after a single dose (UK Ilaxten SmPC).