سعر اوجمنتين 1125مجم 1جم/125مجم 12 كيس لعمل معلق شرب كبار 2025

Augmentin adults 1 g/125 mg (amoxicillin 1000 mg + clavulanic acid 125 mg per sachet) powder for oral suspension, 12 single-dose sachets; penicillin with beta-lactamase inhibitor.

• Acute bacterial sinusitis (adequately diagnosed)Population: Adults and childrenBase de données publique des médicaments (ANSM, France)
• Acute otitis mediaPopulation: Adults and childrenBase de données publique des médicaments (ANSM, France)
• Acute exacerbations of chronic bronchitis (adequately diagnosed)Population: Adults and childrenBase de données publique des médicaments (ANSM, France)

• Most commonly reported: diarrhoea, nausea and vomiting; mucocutaneous candidiasis is common.International label, same product · Base de données publique des médicaments (ANSM, France)

• Hypersensitivity to the active substances, to any penicillin or to any excipient.International label, same product · Base de données publique des médicaments (ANSM, France)
• History of a severe immediate hypersensitivity reaction (e.g. anaphylaxis) to another beta-lactam (e.g. a cephalosporin, carbapenem or monobactam).International label, same product · Base de données publique des médicaments (ANSM, France)
• History of jaundice/hepatic impairment due to amoxicillin/clavulanic acid.International label, same product · Base de données publique des médicaments (ANSM, France)

• Serious, occasionally fatal hypersensitivity reactions (including anaphylactoid and severe cutaneous reactions) can occur; hypersensitivity may progress to Kounis syndrome. Drug-induced enterocolitis syndrome (DIES) has been reported mainly in children. Discontinue if an allergic reaction occurs.International label, same product · Base de données publique des médicaments (ANSM, France)
• Convulsions may occur in patients with impaired renal function or on high doses. Avoid if infectious mononucleosis is suspected (morbilliform rash). A generalised febrile erythema with pustules at treatment start may indicate AGEP (stop; contraindicates further amoxicillin).International label, same product · Base de données publique des médicaments (ANSM, France)
• Hepatic events, reported mainly in males and elderly patients and possibly linked to prolonged treatment, may be severe; antibiotic-associated colitis may range from mild to life-threatening. Prolonged prothrombin time can occur with oral anticoagulants.International label, same product · Base de données publique des médicaments (ANSM, France)

• Oral anticoagulants (acenocoumarol, warfarin)Increased INR has been reported; monitor prothrombin time/INR carefully when amoxicillin is added or withdrawn and adjust the anticoagulant dose if needed.Base de données publique des médicaments (ANSM, France)
• MethotrexatePenicillins may reduce methotrexate excretion, potentially increasing its toxicity.Base de données publique des médicaments (ANSM, France)
• ProbenecidConcomitant use is not recommended; probenecid decreases renal tubular secretion of amoxicillin.Base de données publique des médicaments (ANSM, France)

• Animal studies do not indicate direct or indirect harmful effects; in women with preterm premature rupture of membranes, prophylactic amoxicillin/clavulanic acid may be associated with an increased risk of necrotising enterocolitis in neonates. Avoid in pregnancy unless considered essential by the physician.International label, same product · Base de données publique des médicaments (ANSM, France)
• Both substances are excreted in breast milk; diarrhoea and fungal infection of mucous membranes are possible in the breastfed infant (breastfeeding may need to be stopped); the effects of clavulanic acid on the breastfed infant are not known. Use only after benefit/risk assessment.International label, same product · Base de données publique des médicaments (ANSM, France)

• Amoxicillin: Bactericidal penicillin that inhibits bacterial cell-wall biosynthesis; susceptible to degradation by beta-lactamases, which clavulanic acid inhibits.
• Clavulanic acid: Beta-lactam structurally related to the penicillins that inactivates many beta-lactamase enzymes, protecting amoxicillin from degradation and extending its antibacterial spectrum.