سعر باكتيسفدين 125مجم/5مل معلق 60 مل 2022

Cefdinir 125 mg/5 mL powder for oral suspension, 60 mL bottle after reconstitution; oral third-generation cephalosporin antibacterial (Sigma Tec, Egypt).

• Acute bacterial otitis mediaPopulation: Pediatric patients 6 months-12 yearsDailyMed (U.S. National Library of Medicine)
• Pharyngitis/tonsillitis caused by Streptococcus pyogenesPopulation: Pediatric patients, adults and adolescentsDailyMed (U.S. National Library of Medicine)
• Uncomplicated skin and skin structure infectionsPopulation: Pediatric patients, adults and adolescentsDailyMed (U.S. National Library of Medicine)

• Pediatric suspension trials: diarrhoea 8%, rash 3%, vomiting 1%; diarrhoea (17%) and mainly diaper rash (8%) were more frequent in children 2 years or younger. Reddish stools have been reported, often with iron-containing products.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Postmarketing (rare): anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis, hepatitis/cholestasis, pseudomembranous colitis, blood dyscrasias (e.g. thrombocytopenia, haemolytic anaemia) and acute renal failure.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known allergy to the cephalosporin class of antibiotics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ask about previous hypersensitivity to cefdinir, other cephalosporins, penicillins or other drugs; cross-hypersensitivity among beta-lactams may occur in up to 10% of penicillin-allergic patients. Discontinue if an allergic reaction occurs; serious reactions may need epinephrine and emergency measures.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides (Clostridium) difficile-associated diarrhoea, ranging from mild diarrhoea to fatal colitis, may occur up to two months after antibacterial use; evaluate any diarrhoea and stop non-C. difficile antibacterials if needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Prescribing without a proven or strongly suspected bacterial infection is unlikely to help and increases the risk of drug-resistant bacteria; some cephalosporins have triggered seizures, particularly in renal impairment without dose reduction.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Aluminium- or magnesium-containing antacidsReduce cefdinir absorption; give cefdinir at least 2 hours before or after the antacid.DailyMed (U.S. National Library of Medicine)
• Iron supplements and iron-fortified foodsTherapeutic iron reduced cefdinir absorption by up to 80%; separate by at least 2 hours (iron-fortified infant formula has no significant effect). Reddish stools may occur.DailyMed (U.S. National Library of Medicine)
• ProbenecidInhibits renal excretion of cefdinir (about doubled AUC, 54% higher peak, 50% longer half-life).DailyMed (U.S. National Library of Medicine)

• Not teratogenic in rats or rabbits, but there are no adequate and well-controlled studies in pregnant women; use during pregnancy only if clearly needed. Not studied during labour and delivery.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cefdinir was not detected in human breast milk after single 600 mg doses.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefdinir: Bactericidal; like other cephalosporins it inhibits bacterial cell wall synthesis, and it is stable to some but not all beta-lactamases.