سعر افيروفيكتان 250 مجم / 5 مل معلق 60 مل 2022

Cefdinir 250 mg/5 ml oral suspension, 60 ml bottle; third-generation cephalosporin antibiotic (Averroes Pharma, Egypt).

• Acute bacterial otitis media (H. influenzae, S. pneumoniae penicillin-susceptible, M. catarrhalis)Population: Pediatric patients 6 months through 12 yearsDailyMed (U.S. National Library of Medicine)
• Acute maxillary sinusitisPopulation: Adults, adolescents and pediatric patients 6 months through 12 yearsDailyMed (U.S. National Library of Medicine)
• Pharyngitis/tonsillitis caused by Streptococcus pyogenesPopulation: Adults, adolescents and pediatric patientsDailyMed (U.S. National Library of Medicine)

• Pediatric trials (suspension): diarrhea 8%, rash 3% and vomiting 1% were the most frequent treatment-related adverse events; most were mild and self-limiting.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known allergy to the cephalosporin class of antibiotics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity: ask about previous reactions to cephalosporins, penicillins or other drugs; cross-hypersensitivity among beta-lactams may occur in up to 10% of penicillin-allergic patients; stop the drug if an allergic reaction occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides (Clostridium) difficile-associated diarrhea, ranging from mild diarrhea to fatal colitis, may occur; it has been reported more than two months after antibacterial treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Prescribe only for proven or strongly suspected bacterial infections to limit resistance; use with caution in patients with a history of colitis; the suspension contains 2.86 g of sucrose per teaspoon (relevant for diabetic patients).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids containing aluminium or magnesiumReduce cefdinir absorption; give cefdinir at least 2 hours before or after the antacid.DailyMed (U.S. National Library of Medicine)
• Iron supplements (including iron-containing multivitamins)Interfere with absorption; separate by at least 2 hours (iron-fortified infant formula does not significantly interfere).DailyMed (U.S. National Library of Medicine)
• ProbenecidInhibits renal excretion of cefdinir (about doubling of AUC).DailyMed (U.S. National Library of Medicine)

• Label states historical FDA pregnancy category B: not teratogenic in rats or rabbits; no adequate and well-controlled studies in pregnant women; use in pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• After single 600 mg doses, cefdinir was not detected in human breast milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefdinir: Bactericidal; inhibits bacterial cell wall synthesis like other cephalosporins; stable to some but not all beta-lactamases (US label).