سعر باكتروفايت 500مجم 12 قرص 2026

Nitazoxanide 500 mg film-coated tablets, pack of 12; thiazolide antiprotozoal (Gal Pharma, Egypt).

• Diarrhoea caused by Giardia lamblia or Cryptosporidium parvumPopulation: Patients 12 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>=2%): abdominal pain, headache, chromaturia (discoloured urine) and nausea.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Postmarketing reports: diarrhoea, gastro-oesophageal reflux disease, dizziness, dyspnoea, rash and urticaria.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Prior hypersensitivity to nitazoxanide or any other ingredient of the formulation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Not shown to be effective for diarrhoea caused by Cryptosporidium parvum in HIV-infected or immunodeficient patients; not studied for Giardia diarrhoea in these patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Highly plasma protein-bound drugs with narrow therapeutic index (e.g., warfarin)Tizoxanide is >99.9% protein bound; competition for binding sites may occur, so monitor for adverse reactions; patients are advised to avoid concurrent warfarin use.DailyMed (U.S. National Library of Medicine)

• No human pregnancy data to inform a drug-associated risk; no teratogenicity or fetotoxicity in rats and rabbits at exposures 30 and 2 times the maximum recommended human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No information on presence in human milk or effects on the breastfed infant or milk production; weigh the benefits of breastfeeding against the mother's need for the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Nitazoxanide: Antiprotozoal activity is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction essential to anaerobic energy metabolism.