سعر كونفيولكس 300مجم/مل نقط بالفم 100 مل 2023

Convulex 300mg/ml oral drops 100 ml: Sodium valproate (Gerot Pharma > B.P. Pharma).

• Valproate/valproic acid is indicated for epilepsy (seizure disorders) and in some jurisdictions for bipolar mania and migraine prophylaxis — confirm exact Egyptian labeled indications on the local leaflet.Population: Patients with epilepsy / labeled indicationsDailyMed (U.S. National Library of Medicine)

• Common: nausea, tremor, weight gain, hair loss, somnolence; serious: hepatotoxicity, pancreatitis, thrombocytopenia, hyperammonemia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• US valproate labeling contraindicates use in patients with hepatic disease or significant hepatic dysfunction, known urea cycle disorders, and in pregnancy for migraine prophylaxis; boxed warnings include hepatotoxicity, fetal risk (teratogenicity), and pancreatitis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Serious risks: hepatotoxicity (especially young children/combined anticonvulsants), neural-tube and other major congenital malformations, pancreatitis; monitor LFTs and clinical status; avoid abrupt withdrawal.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Carbapenem antibioticsMajorCarbapenems may markedly reduce valproate levels — risk of breakthrough seizures (US labeling class warning).DailyMed (U.S. National Library of Medicine)

• Valproate is teratogenic (neural tube defects and other major malformations; neurodevelopmental risks). US labeling: contraindicated for migraine prevention in pregnancy; use for epilepsy/bipolar only if other medicines are unacceptable. Do not apply US pregnancy text as Egyptian product-specific advice without the Egyptian leaflet.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Sodium valproate: Increases GABA availability and modulates neuronal excitability; exact mechanism multifactorial.