سعر ديبو بروفيرا 150 مجم/مل 1 فيال 2023

Pfizer Depo-Provera medroxyprogesterone acetate 150 mg/mL IM contraceptive injection vial.

• Prevention of pregnancy in females of reproductive potential (US Depo-Provera CI); not recommended as long-term (>2 years) contraception unless other options inadequate.DailyMed (U.S. National Library of Medicine)

• Very common: menstrual irregularities/bleeding changes, amenorrhea with continued use, weight gain, headache, abdominal pain, nervousness, decreased libido.International label, same product · DailyMed (U.S. National Library of Medicine)

• Active thrombophlebitis or history of thromboembolism/cerebrovascular disease; known/suspected breast malignancy; hypersensitivity; significant liver disease; undiagnosed vaginal bleeding.International label, same product · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING: significant loss of bone mineral density with use; greater with longer duration and may not be completely reversible; unknown impact on peak bone mass if used in adolescence/early adulthood.International label, same product · DailyMed (U.S. National Library of Medicine)
• Cases of meningioma reported with repeated/long-term medroxyprogesterone acetate; discontinue if meningioma diagnosed. Does not protect against HIV/STIs.International label, same product · DailyMed (U.S. National Library of Medicine)

• CYP3A4 enzyme inducers (e.g., rifampin, carbamazepine, phenytoin, St John's wort)MajorMay decrease contraceptive effectiveness; counsel backup/alternative contraception.DailyMed (U.S. National Library of Medicine)

• Discontinue if pregnancy occurs; no contraception role in pregnancy. Epidemiologic data have not shown increased major birth-defect risk from early progestin exposure.International label, same product · DailyMed (U.S. National Library of Medicine)
• Detectable in breast milk; milk quality/quantity appear unaffected. In exclusively breastfeeding mothers, initiate during/after sixth postpartum week.International label, same product · DailyMed (U.S. National Library of Medicine)

• Medroxyprogesterone acetate: Inhibits gonadotropin secretion, preventing follicular maturation and ovulation, and thickens cervical mucus.