سعر اليجارد 45 مجم مستودع 6 أشهر للحقن تحت الجلد 2022

Eligard 45 mg 6-month depot powder for subcutaneous injection: leuprorelin acetate polymeric depot (Astellas / Multipharma Egypt). Same brand as US Tolmar ELIGARD 45 mg.

• Treatment of advanced prostate cancer.Population: Adult men with advanced prostate cancerDailyMed (U.S. NLM)

• Most common (≥5%): malaise/fatigue, hot flashes/sweats, testicular atrophy. Injection-site transient burning/stinging and pain common. Decreased bone density with prolonged androgen deprivation.International label, same product · DailyMed (U.S. NLM)

• Known hypersensitivity to GnRH, GnRH agonist analogs, or any component of ELIGARD.International label, same product · DailyMed (U.S. NLM)

• Tumor flare: transient testosterone rise in first 1–2 weeks may worsen symptoms (bone pain, neuropathy, hematuria, obstruction); monitor patients with vertebral metastases/urinary obstruction closely.International label, same product · DailyMed (U.S. NLM)
• Hyperglycemia/diabetes, increased CV risk (MI, sudden death, stroke), QT prolongation, convulsions, and severe cutaneous adverse reactions (SJS/TEN) reported; monitor and manage per clinical practice; interrupt/discontinue if SCAR confirmed.International label, same product · DailyMed (U.S. NLM)

• May cause fetal harm based on animal data and mechanism; expected hormonal changes increase pregnancy-loss risk. Not indicated in females for this label; advise of fetal risk.International label, same product · DailyMed (U.S. NLM)
• Safety not established in females; unknown whether present in human milk; due to potential serious adverse reactions, decide whether to discontinue breastfeeding or the drug.International label, same product · DailyMed (U.S. NLM)

• Leuprorelin acetate: Continuous GnRH agonist exposure suppresses pituitary gonadotropin secretion after an initial flare, reducing testicular steroidogenesis and serum testosterone to castrate levels (US ELIGARD label).