سعر لوبرون ديبوت 3.75مجم/2مل امبول حقن 2022

Lupron Depot 3.75 mg (1-month depot) by Takeda/Abbott (Egypt): leuprolide acetate, a GnRH agonist given monthly by intramuscular injection for endometriosis and, with iron, preoperatively for anaemia caused by uterine fibroids.

• Management of endometriosis, including pain relief and reduction of endometriotic lesions; with norethindrone acetate for initial management of painful symptoms and for recurrence. Total duration with add-back should not exceed 12 months.Population: WomenDailyMed (U.S. National Library of Medicine)
• Concomitant use with iron therapy for preoperative haematologic improvement of women with anaemia caused by uterine fibroids for whom three months of hormonal suppression is deemed necessary.Population: WomenDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>10%) in clinical trials: hot flashes/sweats, headache/migraine, vaginitis, depression/emotional lability, general pain, weight gain/loss, nausea/vomiting, decreased libido and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to GnRH, GnRH agonist analogs (including leuprolide acetate) or any excipients; undiagnosed abnormal uterine bleeding; pregnancy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Loss of bone mineral density, some possibly irreversible, limits treatment duration; norethindrone add-back reduces BMD loss in endometriosis; assess BMD before retreatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Embryo-fetal toxicity: exclude pregnancy before starting if clinically indicated, discontinue if pregnancy occurs, and use non-hormonal contraception only.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Severe cutaneous adverse reactions (SJS/TEN) and hypersensitivity reactions including anaphylaxis have been reported; when given with norethindrone acetate, its warnings also apply.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy; may cause fetal harm.International label, same formulation · DailyMed (U.S. National Library of Medicine)

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