سعر فينكار 5مجم 10 قرص 2022

Finasteride 5 mg film-coated tablets, pack of 10, by Rameda (Egypt); 5-alpha-reductase inhibitor.

• Treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate, to improve symptoms and reduce the risk of acute urinary retention and of surgery (including TURP and prostatectomy).Population: Adult menDailyMed (U.S. National Library of Medicine)
• In combination with the alpha-blocker doxazosin, to reduce the risk of symptomatic progression of BPH.Population: Adult menDailyMed (U.S. National Library of Medicine)

• Most frequent adverse reactions relate to sexual function: impotence, decreased libido, decreased ejaculate volume and ejaculation disorder; breast enlargement, breast tenderness and rash were also reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Post-marketing reports: hypersensitivity reactions (pruritus, urticaria, angioedema), testicular pain, haematospermia, sexual dysfunction continuing after stopping treatment, male infertility or poor semen quality, depression, suicidal ideation and male breast cancer.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the medicine.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pregnancy: contraindicated in females who are or may become pregnant, because it may cause abnormal external genitalia in a male fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Reduces serum PSA by about 50% within six months; establish a new PSA baseline after six months and evaluate any confirmed PSA rise, which may signal prostate cancer.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• 5-alpha-reductase inhibitors may increase the risk of high-grade (Gleason 8-10) prostate cancer; finasteride is not approved for prostate cancer prevention.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Women who are or may be pregnant should not handle crushed or broken tablets; if contact occurs, wash the area immediately with soap and water.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cytochrome P450-metabolised medicines (e.g. antipyrine, digoxin, propranolol, theophylline, warfarin)No interactions of clinical importance identified; finasteride does not appear to affect the cytochrome P450 drug-metabolising system.DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnant females and not indicated in females; based on animal studies and its mechanism, it may cause abnormal development of the external genitalia of a male fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not indicated for use in females.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Finasteride: Competitive, specific inhibitor of type II 5-alpha-reductase, the enzyme converting testosterone to dihydrotestosterone (DHT); lowers DHT and shrinks the enlarged prostate; no affinity for the androgen receptor.