سعر فلاجيمسين 20 قرص 2022

Flagymycin film-coated tablets (metronidazole + spiramycin; strengths not verified), International Drug Industries / Haya Pharm, Egypt; box of 20 tablets.

• Curative treatment of odonto-stomatological infections such as dental abscess, when another antibiotic cannot be used (French indication for the fixed spiramycin–metronidazole combination).Population: Adults and children aged 6 years and overANSM (Agence nationale de sécurité du médicament), France

• Abdominal pain, nausea, vomiting, diarrhoea, rash; spiramycin: QT prolongation and ventricular arrhythmias (frequency unknown); metronidazole: metallic taste, neurological and haematological effects.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• Hypersensitivity to spiramycin, metronidazole or other imidazoles; children under 6 years (tablet form).General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• Weigh the need for a fixed combination when monotherapy would suffice; anaphylaxis and severe skin reactions (SJS, TEN, AGEP) reported — stop and never re-expose; encephalopathy/cerebellar syndrome and peripheral neuropathy with metronidazole; avoid alcohol.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• AlcoholAntabuse effect from the metronidazole component; avoid alcohol and alcohol-containing medicines.ANSM (Agence nationale de sécurité du médicament), France
• Torsadogenic (QT-prolonging) drugsSpiramycin increases the risk of ventricular arrhythmias including torsades de pointes.ANSM (Agence nationale de sécurité du médicament), France
• Levodopa/carbidopaSpiramycin inhibits carbidopa absorption, lowering levodopa levels; monitor and adjust.ANSM (Agence nationale de sécurité du médicament), France

• French SmPC: use may be considered during pregnancy if needed, whatever the term.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France
• Both metronidazole and spiramycin pass into breast milk; avoid during breastfeeding.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

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