سعر رودوجيل 20 ق 2026

Film-coated tablets of spiramycin 750,000 IU + metronidazole 125 mg, 20 tablets, used for odonto-stomatological (mouth and dental) infections.

• Curative treatment of odonto-stomatological infections such as dental abscesses in adults and children, after benefit-risk assessment and when another antibiotic cannot be used.ANSM - Base de données publique des médicaments

• Spiramycin: common abdominal pain, nausea, vomiting, diarrhoea, rash; frequency unknown QT prolongation/torsades de pointes, anaphylaxis, cholestatic hepatitis, haemolytic anaemia.International label, same formulation · ANSM - Base de données publique des médicaments
• Metronidazole: neutropenia, agranulocytosis, thrombocytopenia; psychiatric reactions; peripheral sensory neuropathy, headache, dizziness, convulsions, encephalopathy; transient visual disturbances.International label, same formulation · ANSM - Base de données publique des médicaments

• Hypersensitivity to spiramycin, metronidazole, other imidazoles or any excipient.International label, same formulation · ANSM - Base de données publique des médicaments
• Children under 6 years (dosage form).International label, same formulation · ANSM - Base de données publique des médicaments
• Concomitant use with certain drugs that can induce torsades de pointes (e.g. amiodarone, citalopram, escitalopram, domperidone, hydroxyzine, moxifloxacin, quinidine, sotalol, IV erythromycin).International label, same formulation · ANSM - Base de données publique des médicaments

• A fixed spiramycin-metronidazole combination should be weighed against monotherapy, which suits most odonto-stomatological infections.International label, same formulation · ANSM - Base de données publique des médicaments
• Allergic reactions including anaphylactic shock and severe skin reactions (Stevens-Johnson syndrome, Lyell syndrome, AGEP) have been reported; stop treatment and do not re-administer.International label, same formulation · ANSM - Base de données publique des médicaments
• Stop metronidazole if signs of encephalopathy or cerebellar syndrome occur (ataxia, dysarthria, gait disturbance, nystagmus, tremor, confusion, convulsions, peripheral neuropathy).International label, same formulation · ANSM - Base de données publique des médicaments

• Alcohol (drinks or alcohol-containing medicines)Disulfiram-like (antabuse) effect with metronidazole; avoid alcohol.ANSM - Base de données publique des médicaments
• DisulfiramRisk of acute psychosis or confusional state.ANSM - Base de données publique des médicaments
• Busulfan (high dose)Metronidazole can double busulfan concentrations.ANSM - Base de données publique des médicaments

• Use may be considered during pregnancy if needed, whatever the term; no particular malformative or fetotoxic effect reported for metronidazole or spiramycin.International label, same formulation · ANSM - Base de données publique des médicaments
• Metronidazole and spiramycin pass into breast milk; avoid during breastfeeding.International label, same formulation · ANSM - Base de données publique des médicaments