سعر اديباكت 550 مجم 20 اقراص 2023

Rifaximin 550 mg film-coated tablets (Idibact; International Drug Industries > Novell Pharma, Egypt); pack of 20 tablets.

• Reduction in risk of overt hepatic encephalopathy recurrence in adults.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hepatic encephalopathy (6-month trial, >=5% and more than placebo): peripheral oedema, nausea, dizziness, fatigue, ascites, muscle spasms, pruritus, abdominal pain, anaemia, depression, nasopharyngitis, arthralgia, dyspnoea, pyrexia, rash.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• IBS-D trials: ALT increased and nausea (about 2-3%, more than placebo).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to rifaximin, any rifamycin antimicrobial agent or any component (reactions have included exfoliative dermatitis, angioneurotic oedema and anaphylaxis).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Not effective in travelers' diarrhoea complicated by fever and/or blood in stool or caused by pathogens other than E. coli (e.g. Campylobacter jejuni; not proven for Shigella/Salmonella); discontinue if symptoms worsen or persist beyond 24-48 hours.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea has been reported and may range from mild diarrhoea to fatal colitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Prescribing without a proven or strongly suspected bacterial infection increases the risk of drug-resistant bacteria.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• P-glycoprotein inhibitors (e.g. cyclosporine)Cyclosporine significantly increased systemic rifaximin exposure; use caution, especially in hepatic impairment.DailyMed (U.S. National Library of Medicine)
• WarfarinINR changes reported; monitor INR and prothrombin time and adjust warfarin as needed.DailyMed (U.S. National Library of Medicine)

• No human pregnancy data; teratogenic effects (ocular, oral/maxillofacial, cardiac and lumbar spine malformations) were observed in rats and rabbits.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No information on presence in human milk or effects on the breastfed infant or milk production; weigh benefits against maternal need.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Rifaximin: Binds the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis.