سعر فلوراسيرتا 5مجم 20 قرص 2022

Levocetirizine 5 mg tablets, pack of 20 (2 strips), by Medizen (Egypt); second-generation antihistamine.

• Symptomatic treatment of allergic rhinitis (including persistent allergic rhinitis) and urticaria in adults and children aged 6 years and above.Population: Adults and children 6 years and overelectronic medicines compendium (eMC)
• Antihistamine (Medizen product page).Medizen Pharmaceutical Industries (manufacturer website)

• Common (adults and adolescents): somnolence (5.2%), headache (2.6%), dry mouth (2.6%) and fatigue (2.5%); uncommon: asthenia and abdominal pain.International label, equivalent formulation · electronic medicines compendium (eMC)
• Post-marketing (frequency not known): hypersensitivity including anaphylaxis, aggression, agitation, convulsion, palpitations, urinary retention, hepatitis, angioneurotic oedema, weight increase and pruritus after discontinuation.International label, equivalent formulation · electronic medicines compendium (eMC)

• Hypersensitivity to levocetirizine, cetirizine, hydroxyzine, other piperazine derivatives or any excipient.International label, equivalent formulation · electronic medicines compendium (eMC)
• End-stage renal disease (eGFR below 15 ml/min, requiring dialysis).International label, equivalent formulation · electronic medicines compendium (eMC)

• Caution with alcohol.International label, equivalent formulation · electronic medicines compendium (eMC)
• Caution in patients predisposed to urinary retention (e.g. spinal cord lesion, prostatic hyperplasia).International label, equivalent formulation · electronic medicines compendium (eMC)
• Caution in epilepsy and in patients at risk of convulsions (possible seizure aggravation).International label, equivalent formulation · electronic medicines compendium (eMC)

• Alcohol and other CNS depressantsMay further reduce alertness and impair performance in sensitive patients.electronic medicines compendium (eMC)
• RitonavirIncreased cetirizine (racemate) exposure by about 40%.electronic medicines compendium (eMC)
• TheophyllineSmall (16%) decrease in cetirizine clearance at theophylline 400 mg daily.electronic medicines compendium (eMC)

• Limited data with levocetirizine; large data with cetirizine show no malformative or feto/neonatal toxicity; use may be considered during pregnancy if necessary.International label, equivalent formulation · electronic medicines compendium (eMC)
• Cetirizine passes into human milk, so levocetirizine excretion is likely and adverse reactions may be seen in breastfed infants; use with caution.International label, equivalent formulation · electronic medicines compendium (eMC)

• Levocetirizine: The (R)-enantiomer of cetirizine; potent, selective antagonist of peripheral H1 receptors with about twice the affinity of cetirizine (UK Xyzal SmPC, section 5.1).