سعر فلودارا 10مجم 20 قرص 2022

Fludarabine phosphate 10 mg film-coated tablets, a purine analogue antineoplastic used for B-cell chronic lymphocytic leukaemia.

• B-cell chronic lymphocytic leukaemia (CLL) in adults with sufficient bone marrow reserves; first-line use only in advanced disease (Rai III/IV, Binet C) or Rai I/II (Binet A/B) with disease-related symptoms or progressive disease.Population: Adultsemc (medicines.org.uk)

• Hypersensitivity to fludarabine phosphate or any excipient; creatinine clearance below 30 ml/min; decompensated haemolytic anaemia; lactation.International label, same product · emc (medicines.org.uk)

• Severe and cumulative bone marrow suppression (anaemia, thrombocytopenia, neutropenia), sometimes fatal pancytopenia; monitor blood counts regularly.International label, same product · emc (medicines.org.uk)
• Life-threatening and sometimes fatal autoimmune haemolytic anaemia and other autoimmune phenomena may occur; stop treatment if haemolysis occurs.International label, same product · emc (medicines.org.uk)
• Neurotoxicity, including leukoencephalopathy and posterior reversible leukoencephalopathy syndrome, can occur; high doses have caused blindness, coma and death.International label, same product · emc (medicines.org.uk)

• Fludarabine phosphate is genotoxic and was embryotoxic and fetotoxic in animals; it must not be used during pregnancy unless clearly necessary; women of childbearing potential should avoid pregnancy and use effective contraception.International label, same product · emc (medicines.org.uk)
• Contraindicated during breastfeeding.International label, same product · emc (medicines.org.uk)

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