سعر جابسولوكس 150 مجم 10 كبسولات 2022

Pregabalin 150 mg capsules, pack of 10, by Spimaco Misr (Egypt), a gabapentinoid used for neuropathic pain and as add-on therapy for partial seizures.

• Neuropathic pain associated with diabetic peripheral neuropathy; postherpetic neuralgia; adjunctive therapy for partial-onset seizures (patients 1 month and older); fibromyalgia; neuropathic pain associated with spinal cord injury.Population: Adults (partial-onset seizures: 1 month and older)DailyMed (U.S. National Library of Medicine)

• Most common: dizziness, somnolence, dry mouth, oedema, blurred vision, weight gain and abnormal thinking (primarily difficulty with concentration/attention).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to pregabalin or any of its components.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Angioedema and hypersensitivity reactions: discontinue immediately if they occur.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs increase the risk of suicidal thoughts or behaviour; monitor for depression or unusual mood changes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Respiratory depression may occur with opioids or other CNS depressants, or in patients with underlying respiratory impairment and the elderly.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Opioids and other CNS depressantsIncreased risk of respiratory depression and additive CNS depressant effects.DailyMed (U.S. National Library of Medicine)

• Observational data suggest a possible small increase in the rate of major birth defects with pregabalin exposure in the first trimester; neonatal withdrawal may occur with combined opioid use.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Pregabalin is present in human milk (about 76% of maternal plasma concentrations; estimated average infant dose 0.31 mg/kg/day); effects on the breastfed infant are unknown.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Pregabalin: Binds with high affinity to the alpha-2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues; the exact mechanism is not fully known.